bradyzoite


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bra·dy·zo·ite

(brad'ē-zō'īt),
A slowly multiplying encysted form of sporozoan parasite typical of chronic infection with Toxoplasma gondii. It has also been called a merozoite or zoite; the complex of bradyzoites within an enclosing membrane has also been called a pseudocyst, though it is now regarded as a true cyst.
[brady- + G. zōē, life]

bra·dy·zo·ite

(brad'ē-zō'īt)
Toxoplasma gondii life-cycle stage that forms within a cystlike structure. The organisms multiply slowly but may be transformed into tachyzoites when the host's immune system is impaired.
[brady- + G. zōē, life]

bradyzoite

small comma-shaped form of Toxoplasma gondii found in tissues enclosed in a pseudocyst; a stage which replicates slowly.
References in periodicals archive ?
Neospora caninum is a cyst-forming parasite and its development involves two asexual stages-tachyzoite and bradyzoite that occur in the intermediate host (e.
gondii is found in three morphologically different strains which are named as tachyzoite, bradyzoite, and sporozoite.
Stage conversion between tachyzoite and bradyzoite forms of Toxoplasma is associated with morphological and molecular biological changes, including stage-specific antigen expression and alterations to metabolism [8].
Scientists working in various fields, including microbiology, in Europe, the US, Japan, and Brazil contribute 26 chapters on its history and life cycle, the molecular epidemiology and population structure, human infection, ocular disease, toxoplasmosis in wild and domestic animals, animal models and therapeutics, biochemistry and metabolism, calcium storage and homeostasis, the role of secretory proteins, the parasite's structures, host immune responses, nucleotide and amino acid metabolism in comparison to other Apicomplexa, bradyzoite development, chemical biology, cerebral toxoplasmosis, innate and adaptive immunity, and vaccination.
They travel in blood and reach different body parts and transformed into bradyzoite cysts (5-10 um diameter) present in skeletal muscles and neural tissues.
In an effort to evade host defenses, tachyzoites switch to a slower growing bradyzoite where they are able to lay dormant.
The organism exits in nature in many forms: macro- and microgametes, the oocyte (which releases sporozoites), the tissue cyst, which contains and may release bradyzoite, and tachyzoite.
Toxoplasma gondii: DNA vaccination with bradyzoite antigens induces protective immunity in mice against oral infection with parasite cysts.
In an immuno competent individual the organism will encyst itself in the brain muscle and eye as a bradyzoite (Burney 1996).
Oocyst shedding by cats fed isolated bradyzoites and comparison of infectivity of bradyzoites of the VEG strain Toxoplasma gondii to cats and mice.
This may occur in the acute phase of infection or, alternatively, when there is recrudescence of encysted bradyzoites, with possible appearance of clinical signs, such as in situations in which the immune system is affected (DUBEY, 2010).