bradyzoite


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bra·dy·zo·ite

(brad'ē-zō'īt),
A slowly multiplying encysted form of sporozoan parasite typical of chronic infection with Toxoplasma gondii. It has also been called a merozoite or zoite; the complex of bradyzoites within an enclosing membrane has also been called a pseudocyst, though it is now regarded as a true cyst.
[brady- + G. zōē, life]

bra·dy·zo·ite

(brad'ē-zō'īt)
Toxoplasma gondii life-cycle stage that forms within a cystlike structure. The organisms multiply slowly but may be transformed into tachyzoites when the host's immune system is impaired.
[brady- + G. zōē, life]

bradyzoite

small comma-shaped form of Toxoplasma gondii found in tissues enclosed in a pseudocyst; a stage which replicates slowly.
References in periodicals archive ?
Scientists working in various fields, including microbiology, in Europe, the US, Japan, and Brazil contribute 26 chapters on its history and life cycle, the molecular epidemiology and population structure, human infection, ocular disease, toxoplasmosis in wild and domestic animals, animal models and therapeutics, biochemistry and metabolism, calcium storage and homeostasis, the role of secretory proteins, the parasite's structures, host immune responses, nucleotide and amino acid metabolism in comparison to other Apicomplexa, bradyzoite development, chemical biology, cerebral toxoplasmosis, innate and adaptive immunity, and vaccination.
In an effort to evade host defenses, tachyzoites switch to a slower growing bradyzoite where they are able to lay dormant.
Histopathology revealed severe pulmonary congestion and edema, and interstitial mononuclear cell inflammation associated with many cysts that contained bradyzoites of Toxoplasma gondii scattered throughout.
84) Histologic features vary from nonspecific inflammation to necrosis, and pseudocysts with tachyzoites, as well as cysts with bradyzoites, may be seen (Figure 4, h).
All homoeothermic animals can be intermediary hosts, where the asexual reproduction of the parasite occurs with the formation of tachyzoites and bradyzoites (JACOBS, 1967; DUBEY, 1994).
Attempts were made to culture sarcocysts from muscle tissue homogenates in U937 and THP-1 human monocytic cell lines but no propagation of bradyzoites was obtained.