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bradykinin

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bradykinin /brady·ki·nin/ (-ki´nin) a nonapeptide kinin formed from HMW kininogen by the action of kallikrein; it is a very powerful vasodilator and increases capillary permeability; in addition, it constricts smooth muscle and stimulates pain receptors.
brad·y·ki·nin (brd-knn, -knn)
n.
A biologically active polypeptide that forms from a blood plasma globulin and mediates the inflammatory response, increases vasodilation, and causes contraction of smooth muscle. Also called kallidin I.

bradykinin (brā´dkī´nin),
n one of a number of plasma kinins, a potent vasodilator; physiologic mediators of an anaphylactic reaction.

bradykinin
a nonapeptide kinin formed from a plasma protein, high-molecular-weight (HMW) kininogen, by the action of kallikrein; it is a very powerful vasodilator that increases capillary permeability and, in addition, constricts smooth muscle and stimulates pain receptors.

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Carrageenan inflammation increases bradykinin sensitivity of rat cutaneous nociceptors.
Effect of bradykinin on allergen induced increase in exhaled nitric oxide in asthma.
Moreover, when capsaicin or another chemical called bradykinin was applied to the hearts of rats, the animals' blood pressure and heart-nerve activity increased in a manner similar to that seen in heart attacks.
 
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