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border disease

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border disease
an infectious disease of sheep originally described in the Anglo-Scottish border area of the United Kingdom, but subsequently reported from most of the major sheep-producing countries. Caused by a pestivirus (border disease virus) and manifest with abortion, stillbirths, barren ewes and the birth of small weak lambs some of which have an abnormally hairy birth coat, gross tremor of skeletal muscles, inferior growth and a variable degree of skeletal deformity. The disease results from congenital infection and affected sheep are persistently infected. Called also hairy shaker disease.

border disease virus (BDV)
a pestivirus in the family Flaviviridae.


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Confusing clinical signs in sheep underline the need for developing diagnostic tests to discriminate between bluetongue and other confounding diseases such as contagious ecthyma, border disease, and foot-and-mouth disease.
Establishing environmental links to border diseases such as cancer, systemic lupus erythematosus, and neural tube defects is difficult.
 
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