Orthobiologics: Demineralised Bone Matrix (DBM), Growth Factor Proteins, Bone Morphogenetic Proteins
, Stem Cells
The combination of surface topographies is designed to create an optimal host-bone response and actively participate in the fusion process by promoting the up-regulation of osteogenic and angiogenic factors necessary for bone growth, encouraging natural production of bone morphogenetic proteins
, and "creating the potential for a faster and more robust fusion," the company claims.
A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins
Effect of transforming growth factor beta and bone morphogenetic proteins
on rat hepatic stellate cell proliferation and trans-differentiation.
Specialists in biomaterials in the US, Asia, and Europe address different types of nanobiomaterials, how to generate porous biomaterials for tissue engineering, calcium phosphate-based biomaterials intended for mineralized tissue regenerative applications, the nanocrystalline form of calcium phosphates, the design and fabrication of silicon dioxide nanoparticles, new kinds of titanium alloy implants, an injectable growth factor system based on bone morphogenetic proteins
, impedance sensing of biological processes in mammalian cells, hydrogels-based implantable glucose sensors, the molecular design of multifunctional polymers for gene transfection, hydrogels and their potential biomedical applications, and hybrid biomaterials with high mechanical and biological properties.
Osseolive[R] has been specifically designed for the treatment of large defects in combination with bone growth supporting substances, such as bone marrow aspirate, stem cells, and bone morphogenetic proteins
US: Manufacturer of Ostinol[TM] Bone Morphogenetic Proteins
Expression of bone morphogenetic proteins
in fracture healing.
This repellant is mediated by bone morphogenetic proteins
Bone morphogenetic proteins
(BMPs), which belong to the transforming growth factor [beta] (TGF-[beta]) superfamily, form dimers that are interconnected by seven disulfide bonds (Knight and Glister, 2006).
This monograph is a summary of basic principles for bone repair and bone grafts for autografts, allografts and graft substitutes and includes coverage of the biology of bone grafts, demineralized bone matrix and synthetic bone graft substitutes, the role of bone morphogenetic proteins
, bone marrow and bone marrow products as osteogenic aids, massive allograft transplantation following tumor resection, spinal fusion, allografts in adult hip and knee reconstruction, novel options and bone graft decision making.
The process of demineralization apparently releases bone morphogenetic proteins
from the bone matrix, allowing these potent factors to induce stromal cells in the adjacent tissue to differentiate along osteoblast lineage.