bone morphogenetic protein-7

bone morphogenetic protein-7

A protein encoded by BMP7 on chromosome 20q13, which plays a key role in cartilage formation, osteoblast differentiation, renal development and repair, and induces the production of SMAD1.
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On the basis of type, the global bone morphogenetic protein market is sub divided into recombinant bone morphogenetic protein-7 (rhBMP-7) and recombinant bone morphogenetic protein-2 (rhBMP-2).
Mariel Therapeutics is a clinical stage biopharmaceutical company focused on the clinical application of Bone Morphogenetic Protein-7 (BMP-7) in osteoarthritis, chronic kidney disease, and Alport's Syndrome.
Bone morphogenetic protein-7 (BMP-7; also called osteogenic protein-1), is a member of the Transforming Growth Factor b (TGF-b) superfamily, which was originally isolated from bone (1-3).
Expression, purification, bioactivity, and partial characterization of a recombinant human bone morphogenetic protein-7 produced in human 293T cells.
Cook SD, Baffes GC, Wolfe MW, Sampath TK, Rueger DC: Recombinant human bone morphogenetic protein-7 induces healing in a canine long-bone segmental defect model.
The mice were treated with injections of bone morphogenetic protein-7 (BMP-7), a treatment Hruska found in previous research could prevent bone weakening in mice whose kidneys had been damaged or removed.
M2 EQUITYBITES-July 8, 2014-Mariel Therapeutics to acquire Stryker's Bone Morphogenetic Protein-7 assets
a clinical stage biopharmaceutical company, announced yesterday that it has signed a definitive agreement to acquire Stryker Corporation's (NYSE: SYK) Bone Morphogenetic Protein-7 (BMP-7) assets.
M2 PHARMA-July 8, 2014-Mariel Therapeutics to acquire Stryker's Bone Morphogenetic Protein-7 assets
8 July 2014 - US clinical stage biopharmaceutical company Mariel Therapeutics Inc said it had agreed to buy medical technology firm Stryker Corp's (NYSE:SYK) bone morphogenetic protein-7 (BMP-7) assets for the potential treatment of osteoarthritis (OA), chronic kidney disease (CKD) and other organ fibrosis conditions, lupus, and obesity.
Paul Krebsbach, DDS and colleagues from the University of Michigan School of Dentistry in Ann Arbor used an adenovirus vector engineered to express bone morphogenetic protein-7 (BMP-7) to transduce human gingival or rat dermal fibroblasts.
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