bone marrow aspiration


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bone marrow aspiration

Removal of bone marrow fluid via a needle to diagnose a number of conditions, including leukemia, lymphoma, and multiple myeloma. Bone marrow aspiration is also used for bone marrow transplantation. See bone marrow transplantation.

bone marrow

the soft, organic material in the cavities of bones, a network of blood vessels and special connective tissue fibers that hold together a composite of fat and blood-producing cells.
The chief function of bone marrow is to manufacture erythrocytes, leukocytes and platelets. These blood cells normally do not enter the bloodstream until they are fully developed, so that the bone marrow contains cells in all stages of development. If the body's demand for white cells is increased because of infection, the bone marrow responds immediately by increasing production. The same is true if more red blood cells are needed, as in hemorrhage or anemia.
There are two types of bone marrow, red and yellow. The former produces the blood cells; the latter, which is mainly formed of fatty tissue, normally has no blood cell-producing function.

bone marrow aplasia
any of the three cell lines may be singularly aplastic but a pancytopenic abnormality is most common. See also aplastic anemia.
bone marrow aspiration
see bone marrow biopsy.
congenital bone marrow hypoplasia
bone marrow-derived cells
see B lymphocyte.
bone marrow displacement
bone marrow dyscrasia
abnormal cell production by the bone marrow. Occurs in some dog breeds, especially Poodles, in which there are maturation abnormalities of erythrocytes with macrocytosis and hypersegmented neutrophils.
bone marrow spaces
the cavities in cancellous bone that are usually filled with bone marrow.
bone marrow suppression
some drugs and infectious agents can cause reduced erythropoiesis, myelopoiesis and megakaryocytopoiesis. See also anemia, pancytopenia.
toxic bone marrow arrest
see resurgence granulopoiesis.
bone marrow transplantation
the transfer of bone marrow from a normal, antigenically matched individual to another, usually for treatment of aplastic anemia, immunodeficiency or metabolic disorders.
References in periodicals archive ?
A pathologist's perspective on bone marrow aspiration and biopsy, I: performing a bone marrow examination.
Multiple histiocytes with hemophagocytosis and myeloid hyperplasia were observed on bone marrow aspiration.
In contrast to intracoronary infusion of autologous bone marrow mononuclear CD34+ cells (MNCCD34+) mobilization by G-CSF differs in various ways: first, MNCCD34+ mobilization is noninvasive and requires only subcutaneous injections; second, bone marrow aspiration and preparation is not required (potentially difficult in acute patients);third, repeat catheterization with intracoronary infusion is avoided; fourth, exposure to both G-CSF and to mobilized MNCCD34+ begins early after reperfusion in the susceptible phase (25,26); and fifth, exposure of post-ischemic injured myocardium to mobilized MNCCD34+ is sustained over 1 week at concentrations markedly exceeding natural cell mobilization in acute infarction.
In brucella endemic countries, it seems rational to wait for the results of agglutination tests in the differential diagnosis of isolated, mild to moderate thrombocytopenia before performing a bone marrow aspiration, particularly for children over 10 years old.
Bone marrow aspiration and biopsy was performed because of the suspicion for myeloma, which showed normocelluar marrow with no evidence of myeloma.
Bone marrow aspiration cytology revealed normal cellularity, with myeloid, erythroid, and megakaryocyte cell lines present.
Bone marrow aspiration and biopsy showed 90% plasma cell infiltration and CD38 and kappa were positive.
com)-- Biologic Therapies, a medical device company specializing in the design and manufacturing of proprietary, groundbreaking medical components, has received clearance from the Food and Drug Administration (FDA) to begin marketing its new Bio-MACTM Bone Marrow Aspiration Catheter.
Conrad had the recommended tests - a bone marrow aspiration and biopsy of the blood, marrow, bone fragments and lymph nodes, labs and CT/PET/MRI scans to see if the cancer had spread.
3,4) After a tissue diagnosis has been made, the patient should undergo a full metastatic work-up, including a chest x-ray, CT of the lungs, a bone scan, and bone marrow aspiration to ascertain whether the tumor has metastasized.
Bone marrow aspiration and biopsy revealed numerous noncaseating granulomas, active hematopoiesis, and 4% plasma cells (slides not available for review).
22),calibre dental needle in g: 27 x 1 1/4 (high); esterilizarle: yes; form: tribiselada; siliconized: yes; pyrogen-free: yes; (dental needle),needle biopsy and bone marrow aspiration special features: for adult; sterile: s; (send sample),needle for spinal block special features: no.