bolus thrombolytic

bolus thrombolytic

A a thrombolytic (e.g., tPA) which is administered as a bolus to reduce time to effect and mortality in acute MI.

bolus thrombolytic

Cardiology noun A thrombolytic–eg, tPA, administered as a bolus–ie, to ↓ time to treatment and ↓ mortality in acute MI See ASSENT I, Bolus, TNK-tPA.
References in periodicals archive ?
Bolus thrombolytic agents like reteplase are available and much better suited than tissue plasminogen activator for use in the prehospital arena.
In ASSENT 4 PCI, we are examining whether AMI patients facing a delay prior to PCI may be better served by receiving a bolus thrombolytic plus heparin, which can be given immediately, followed by PCI when it becomes possible," said Dr.
In February 2000, Actelion and Genentech signed an agreement to develop and co-promote Veletri for the treatment of AHF, and to co-promote Genentech's new single bolus thrombolytic TNKase(TM) (tenecteplase).