bolus injection

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bolus injection

The injection of drug in a single large volume (a bolus), as in an IV infusion, in contrast to gradual administration.
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When shock is diagnosed fluid resuscitation should commence with a rapid (over 5 - 10 min) bolus infusion of 20 ml/kg isotonic crystalloid, e.
The Cetuximab Combined with Irinotecan in First Line Therapy for Metastatic Colorectal Cancer (CRYSTAL) and the Bolus Infusion Capecitabine Camptosar with Celebrex (BICC-C) studies are two large trials that have reported results from first-line treatment combination of cetuximab and FOLFIRI.
Eleven patients used complex or periodic bolus infusion modes and most (54%) required more than 9 months of therapy to achieve total daily dose titration with simple infusion.
Adding a high-dose (25 [micro]g/kg) bolus infusion of tirofiban to standard drug therapy just before high-risk percutaneous coronary interventions cut the rate of ischemic complications in a preliminary (phase II) study.
2] were administered on day 1 of weeks 1 through 6 via bolus infusion following oxaliplatin administration.
The cumulative insulin exposure during the first 60 minutes following a bolus infusion was 64% greater for the Aspart-PH20 formulation compared to aspart alone (p < 0.
Immediately after the recombinant human antithrombin bolus infusion, an intravenous bolus of 2 ng/kg National Reference Endotoxin (LPS, Escherichia coli; USP, Rockville, MD) was given to all subjects.
These pumps allow for the gradual delivery of a drug over a period of days in the privacy of one's home, compared to bolus infusion chemotherapy treatments that are given in a single high dose over a short period of time.
High dose IL-2 was administered as a bolus infusion every 8 hours for a total of 14 doses.
Continuous infusion pumps allow for the gradual delivery of a drug over a period of days in the privacy of one's home, compared to bolus infusion chemotherapy treatments that are given in a single high dose over a short period of time.
In the first study, a 300 mg dose was administered by intravenous (IV) bolus infusion, while in the second study, 90 mg daily doses were given IV for five days.