However, if the exposure had occurred over a number of hours instead of as a bolus dose
as modeled, other possible exposures should be considered [e.
All patients received the systemic bolus dose
of tirofiban 10 mcg/kg either via IC or IV route, followed by a 36 hours of IV infusion at 0.
Is relative reversible adrenal suppression after bolus dose
etomidate in the shocked patient the same for cases of traumatic and other forms of shock as for cases of septic shock?
Alterations to this protocol, with the exception of the bolus dose
, render it inactive.
Recommendations about bolus doses
of oxytocin refer to initial doses only and ongoing assessment of their efficacy, in consultation with the obstetrician, is mandatory.
6] concentrations for diet exposure were scaled to the oral bolus dose
5 [micro]g/kg/h, dexmedetomidine provided more effective sedation as demonstrated by the need for fewer bolus doses
of morphine, a decrease in the 24-hour requirements for supplemental morphine, as well as a decrease in the total number of assessment points with a Ramsay score of 1 (inadequate sedation) and the number of patients who had a Ramsay score of 1.
A total of 2212 patients were randomized to receive either a bolus dose
of tirofiban and then a constant infusion of tirofiban for 36 hours or placebo.
However, because effects of the bolus dose
may last longer, monitoring of vital signs and muscle tone for 24 hours post-bolus may be required.
Among patients treated with an initial bolus dose
Each subject received a single subcutaneous bolus dose
of 10 mg (healthy subjects) and 5 mg (critically ill patients) of oxycodone injected over one minute through a 27 G needle sited in the subcutaneous tissue just below the clavicle.
Information concerning dexmedetomidine included the indication for its administration, the initial bolus dose
(if used), the initial infusion rate (if used), changes in the infusion during administration, duration of administration, and adverse effects that could be attributed to the medication.