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Related to blue sclera: osteogenesis imperfecta
the tough, white outer coat of the eyeball, covering approximately the posterior five-sixths of its surface, continuous anteriorly with the cornea and posteriorly with the external sheath of the optic nerve. adj., adj scle´ral.
blue sclera abnormal blueness of the sclera; it is a prominent feature of osteogenesis imperfecta and is also seen in certain other conditions. (See Atlas 1, Part B.)
DiffDx Blue sclera may also be seen in AIDS embryopathy, Bloch-Sulzberger syndrome, Crouzon syndrome, Cornelia de Lange syndrome, Ehlers-Danlos syndrome, Foelling syndrome, Laron dwarfism—Loja type—Lowe syndrome, Marfan syndrome, pseudohypoparathyroidism, Turner syndrome, and Werner syndrome
An abnormal thinning of the sclera through which a blue uveal pigment is seen. This may be found in people with disorders of collagen formation such as osteogenesis imperfecta.
See also: sclera