FATALITIES HAVE OCCURRED, ALTHOUGH RARELY, DUE TO SEVERE REACTIONS TO SULFONAMIDES INCLUDING STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, FULMINANT HEPATIC NECROSIS, AGRANULOCYTOSIS, APLASTIC ANEMIA AND OTHER BLOOD DYSCRASIAS
Preexisting Blood Dyscrasias
: Patients who have preexisting blood dyscrasias
, such as bone marrow hypoplasia, leukopenia, thrombocytopenia, or significant anemia.
Side effects: Hypersensitivity and allergic reactions including anaphylaxis, skin rash, angioedema, Stevens Johnson syndrome and blood dyscrasias
When it does occur, it may be caused by blood dyscrasias
, sickle-cell disease, anticoagulation therapy, local trauma, leukemia, radiation therapy, or drug abuse; also, some cases are idiopathic.
Although the causal relationship to Enbrel remains unclear, advise patients to seek immediate medical attention if they develop signs and symptoms of blood dyscrasias
Studies have shown no changes in blast and mature neutrophil counts in patients with various blood dyscrasias
who were receiving lithium.
Anemia, blood dyscrasias
, and cryoglobulinemias are rare but may occur.
In addition, there were 43 cases of hearing loss, 30 of glaucoma, 31 disorders of visual refraction, 32 cases of nonhypertensive cardiovascular disease, 32 cases of blood dyscrasias
, and 43 cases of anemia, according to Dr.
The risk of blood dyscrasias
in newborns is low, but they should be checked for such abnormalities.
Hypersensitivity and allergic reactions including anaphylaxis, skin rash, Stevens Johnson Syndrome, blood dyscrasias
Post marketing experience from paracetamol alone: rarely hypersensitivity including skin rash, blood dyscrasias
, including thrombocytopenia and agranulocytosis.
Due to availability of methods to make diagnosis in early stages diseases such as gout, blood dyscrasias
and malignancies are not seen radiographically in late stages.