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blocking antibody

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
blocking antibody
n.
1. An antibody that combines with an antigen without a reaction but that blocks another antibody from later combining with that antigen.
2. An immunoglobulin that combines specifically with an atopic allergen but does not elicit an allergic reaction.

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He says the onset of arthritis took two weeks longer in the receptor-antibody-treated mice than in mice not given the blocking antibody.
and his colleagues were the first to show that tumor cells secreted VPF and that a blocking antibody to VPF could prevent the devastating edema and fluid accumulation characteristic of ovarian, breast, and many other human cancers.
Preclinical data suggest that a blocking antibody to HMGB1 may provide protection in chronic diseases, such as rheumatoid arthritis, and in acute life-threatening conditions, such as sepsis.
 
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