blockbuster orphan drug

blockbuster orphan drug

A drug that was originally developed to treat an orphan disease, which can also be used to treat a non-orphan (read, high-volumes) disease, allowing the pharmaceutical company to charge orphan drug prices.

Examples
Human growth hormone (Humatrope, Protropin), erythropoietin (Epogen), pentamidine aerosol (Nebupent), alglucerase (Ceredase), selegiline (Eldepryl).
References in periodicals archive ?
Examples of blockbuster orphan drugs include Novartis' leukaemia drug, Glivec/Gleevec (imatinib), with global sales of US$4,695 million in 2011; and Actelion's Tracleer (bosentan), the current gold standard in pulmonary arterial hypertension with sales of CHF1,522 million (US$1,598 million) in 2011.