bleeding disorder, platelet-type, 13, susceptibility to

(redirected from bleeding disorder due to defective platelet thrombaxane A2 receptor)

bleeding disorder, platelet-type, 13, susceptibility to

A disorder characterised by reduced platelet aggregation and a tendency to mild mucocutaneous bleeding. 

Molecular pathology
Caused by defects of TBXA2R, which encodes a G protein-coupled receptor that interacts with thromboxane A2 to induce platelet aggregation and regulate haemostasis.