Hamilton Thome's LYKOS laser system is used for intricate clinical procedures such as laser-assisted hatching, trophectoderm biopsy and blastomere biopsy
The effects of blastomere biopsy
and oxygen tension on bovine embryo development, rate of apoptosis and interferon-tau secretion.
Because polar-body biopsy is restricted to testing for maternal disease, blastomere biopsy
has gained favor as the method of choice for genetic testing of preimplantation pregnancies.
From the point of view of these critics, human blastomere biopsy
would be akin to creating and destroying an embryo's identical twin for stem cell research.
Chromosomal testing of a blastomere biopsy
can miss problems absent in one cell but present in others.
it offers preimplantation genetic diagnosis with polar body sampling or blastomere biopsy
, and markets its services to couples concerned about passing inherited genetic disorders to their offspring.
like-wise has the disadvantage of removing one or two blastomeres from the 6 to 10 cell embryo, but provides the broadest opportunity for assessing the genetic composition of the embryo.
The ZILOS-tk[R] is now the only non-contact laser device to be awarded marketing clearance for zona-pellucida drilling for blastomere biopsy and trophectoderm biopsy of human embryos in clinical applications.
Both blastomere biopsy and trophectoderm biopsy are used in the practice of preimplantation genetic diagnosis (PGD), which determines the genetic composition of the embryo and ascertains whether it carries any disease-producing mutations.
The 5-probe blastomere biopsy
would have detected about a third of abnormalities and conceivably would have prevented fewer than 20% of the miscarriages in the sample.
West will discuss ACT's recently-published data on blastomere biopsy
(a novel technique that allows human ES cell lines to be produced from a single embryonic cell), thereby demonstrating the feasibility of producing new human ES cell lines without disaggregating human embryos.
CHICAGO -- Blastomere biopsy
of IVF embryos to perform preimplantation genetic analysis may decrease spontaneous abortions due to abnormal karyotype, according to a study presented at the annual meeting of the Society for Gynecologic Investigation.