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blastogenesis |
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blastogenesis /blas·to·gen·e·sis/ (blas″to-jen´ĕ-sis) 1. development of an individual from a blastema, i.e., by asexual reproduction. 2. transmission of inherited characters by the germ plasm. 3. morphological transformation of small lymphocytes into larger cells resembling blast cells on exposure to phytohemagglutinin or to antigens to which the donor is immunized.blastogenet´icblastogen´ic
blastogenesis [blas′tōjen′əsis] Etymology: Gk, blastos + genein, to produce 1 asexual reproduction by budding. 2 the transmission of hereditary characteristics by the germ plasm. Compare pangenesis. 3 the early development of an embryo during cleavage and formation of the germ layers. 4 the process of transforming small lymphocytes in tissue culture into large, blastlike cells by exposure to phytohemagglutinin or other substances, often for the purpose of inducing mitosis. blastogenetic, adj. blastogenesis 1. development of an individual from a blastema, i.e. by asexual reproduction. 2. transmission of inherited characters by the germ plasm. 3. morphological transformation of small lymphocytes into larger cells resembling blast cells on exposure to phytohemagglutin, or to antigens to which the donor is immunized. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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For blastogenesis assays, PBMCS were cultured with CP (10 [micro]g/mL), RBLS (5 [micro]g/mL), or phytohemagglutinin (10 [micro]g/mL). Immersion of chinook salmon eggs in a nominal concentration of o,p'-dichlorodiphenyldichloroethylene (o,p'-DDE; 10 ppm) for 1 hr at fertilization followed by immersion in the same dose for 2 hr at hatch resulted in a significant reduction in the ability of splenic leukocytes from fish 1 year after treatment to undergo blastogenesis upon in vitro stimulation with lipopolysaccharide. For example, Siberian hamsters exposed to short-day photoperiod demonstrate increased natural killer-cell activity and lymphocyte blastogenesis but decreased phagocytosis and oxidative burst activity by granulocytes (40); deer mice treated with melatonin in constant photoperiod exhibit increased lymphocyte response to mitogen stimulation (41). |
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