It is currently being developed for the treatment of recurrent superficial bladder cancer, which is cancer that has not invaded the muscle of the bladder wall
4,5] Previous studies have demonstrated that BOO causes smooth muscle hypertrophy, fibrocyte hyperplasia and collagen deposition in the bladder wall
Recent clinical studies indicate that bladder wall
thickness and related bladder wall
mass may correlate with BOO.
In the urinary bladder, GAG forms a protective barrier between urine and the bladder wall
, defects in this barrier function allow toxins and irritants in the urine to seep through resulting in inflammation of the bladder wall
Subsequent staging investigations, including computed tomography (CT) and bone scan, showed thickening of the right lateral bladder wall
with possible involvement of the distal right ureter, but no evidence of distant metastatic disease.
The patient then underwent rigid cystourethroscopy under spinal anesthesia, with findings of smooth uretha, non-obstructing prostate lobes, mildly trabeculated bladder wall
, normal bilateral ureteral orifice and no active bleeding.
Proctoscopy was negative for a rectal injury, and cysto-urethroscopy demonstrated a left anterolateral bladder wall
defect, where the bullet had entered the bladder, as well as an intravesical bullet (Fig.
The tumour invaded through the bladder wall
and into the perivesicular and peri-prostatic fat.
Unlike transitional cell carcinoma, paragangliomas are mainly located within the bladder wall
and have the characteristics of exogenesis, therefore a transurethral resection of the bladder tumour may not be able to remove the tumour completely and may carry the risk of hemorrhage and recurrence.
Key findings of the preclinical trial -- in which either a Tengion Neo-Bladder Augment or a biodegradable mesh scaffold alone was surgically implanted following partial, trigone-sparing cystectomy and both groups were evaluated clinically at one, three, six and nine months -- show that the Tengion Neo-Bladder Augment restored baseline urodynamics as early as six months after implantation and led to a structurally and functionally complete regenerated bladder wall
as early as nine months.
There are many theories of IC and it may be an allergic reaction to this original infection where the bladder wall
becomes scarred or stiff.
patient with recurrent UTIs and irritative symptoms who was found during cystoscopy to have three errant sutures in the bladder wall
from a previous surgical procedure.