Changes in voided volume, cystometric bladder capacity, bladder compliance
and detrusor contractions were also recorded.
The purpose of this study was to assess the efficacy and safety of ureterocystoplasty in children with a small bladder capacity and low bladder compliance
A medium-term analysis of the subjective efficacy of treatment for women with detrusor instability and low bladder compliance
describes the relationship between the change in volume and change in detrusor pressure and is expressed in millilitres per centimetre of water (ml/cm[H.
It results in loss of bladder compliance
and elasticity, decrease in functional bladder volume, increased storing pressure, loss of contractions and residual urine in the bladder (15).
The underlying mechanisms involve overactive detrusor muscle or poor bladder compliance
The higher artificial filling rates are associated with lower bladder compliance
and higher pressure rises during filling in patients with neurogenic bladder (5,6).
At the 4-week follow-up visit, urodynamic evaluation revealed a significant increase of maximal cystometric bladder capacity, bladder compliance
, volume during first desire to void, and a decrease of daytime frequency.
In female patients, the evaluation must include a complete history and physical examination (including a pelvic examination) and simple cystometrogram to rule out abnormalities of bladder compliance
and abnormalities of urethral support.
Preliminary data relating to bladder compliance
and urinary incontinence was observed during the Phase Ib clinical trial of 12 patients.
This causes proliferation in mucosa, submucosa, detrusor, and serosa and a decrease in bladder compliance
affecting the response of the bladder to filling and contraction.
Patients with poor bladder compliance
, detrusor sphincter dyssynergia or outlet obstruction can develop a functional obstruction due to raised intravesical pressures.