BCNU

(redirected from bis-chlorethylnitrosourea)
Also found in: Dictionary, Encyclopedia.

carmustine

 [kahr-mus´tēn]
a cytotoxic alkylating agent of the nitrosourea group, used as an antineoplastic agent, primarily against brain tumors, multiple myeloma, colorectal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphomas. Called also BCNU.

car·mus·tine

(kar-mŭs'tēn),
An antineoplastic agent.
Synonym(s): BCNU

BCNU

carmustine.

BCNU

BCNU

A chemotherapeutic related to lomustine (CCNU) and semustine, which partially overlaps the activity/toxicity of alkylating agents.
 
Indications
Hodgkin lymphoma, non-Hodgkin lymphoma, melanoma, myeloma, brain tumours, gastrointestinal carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukaemia and brain tumours.
 
Side effects
Nausea, vomiting, decreased platelets, reduced WBCs, secondary leukaemia, pulmonary fibrosis, renal failure.

BCNU

Bis-chlorethylnitrosourea, carmustine A chemotherapeutic related to lomustine–CCNU and semustine, which partially overlaps the activity/toxicity of alkylating agents Indications Hodgkin's disease, possibly NHL, melanoma, myeloma, brain tumors, GI carcinomas; BCNU crosses the blood-brain barrier and may be used for meningeal leukemia and brain tumors Side effects N&V, ↓ platelets, ↓ WBCs, 2º leukemia, pulmonary fibrosis, renal failure

BCNU