Pertaining to or characterized by biphenotypy.


Pertaining to or characterized by biphenotypy.
References in periodicals archive ?
Eight patients (47%) had a history of bone marrow disease before the diagnosis of myeloid sarcoma, including 3 patients (38%) with AML, 2 patients (25%) with MDS, 2 patients (25%) with chronic myelomonocytic leukemia, and 1 patient (13%) with acute biphenotypic T/myeloid cell leukemia.
Pathologic examination reveals a characteristic biphenotypic cell line composed of chief cells and sustentacular cells with a peripheral fibrovascular stromal layer that are organized into a whorled (Zellballen) pattern.
Subtypes include precursor B acute lymphocytic leukemia, precursor T acute lymphocytic leukemia, Burkitt leukemia, and acute biphenotypic leukemia.
In all, 763 cases 645 cases of acute lymphoblastic leukemia (ALL), 102 of acute mveloblastic leukemia (AML), and 16 of undifferentiated or biphenotypic AL] of the 842 eligible cases consented to participate (91%).
PEL cells rarely exhibit genotypic infidelity with biphenotypic B- and T-cell expression (positive B- and T-cell gene rearrangements) (4).
A diagnosis of granular ALL was rendered after evaluation by the EGIL (European Group on Immunologic Classification of Leukemias) biphenotypic system showed the patient to score less than 2 points in the myeloid and T-cell groupings, which mitigates against biphenotypic lineage.
Smoothened expression was detected in lymphoid-lineage cell lines and in the biphenotypic lymphoid/myeloid line Reh.
was diagnosed with biphenotypic leukemia at the age of 14 and endured 20 months of chemotherapy.