biphasic pulmonary blastoma

biphasic pulmonary blastoma

A rare malignant tumour of the lungs which affects adults, average age 43, and is linked to tobacco use.

Clinical findings
Asymptomatic to symptoms of nonspecific lung disease.

Imaging
Usually a large peripheral nodule.

Management
Surgical excision.

Prognosis
Poor; 16% 5-year survival.

Poor prognosticators
Tumour recurrence, metastasis at presentation, tumour > 5 cm, nodal metastasis.
References in periodicals archive ?
If a small biopsy specimen shows only a fetal adenocarcinoma pattern, one cannot exclude the possibility of a biphasic pulmonary blastoma, realizing the blastematous component may not have been sampled.
4,24,26) Recurrence occurs in approximately 43% of biphasic pulmonary blastomas.
Biphasic pulmonary blastomas have both a malignant glandular component and an embryonic or "blastematous" stroma (2,4) (Figure 7).