biperiden


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biperiden

 [bi-per´ĭ-den]
a synthetic anticholinergic used as an antidyskinetic to reduce the tremors of parkinsonism and for the treatment of drug-induced extrapyramidal reactions; administered orally as the hydrochloride salt and intramuscularly or intravenously as the lactate salt. Side effects are minor and include dryness of the mouth, blurring of vision, drowsiness, and nausea. Biperiden is contraindicated in patients with epilepsy and should be given with great care to patients with glaucoma.

biperiden

/bi·per·i·den/ (-per´ĭ-den) an antidyskinetic used as the hydrochloride and lactate salts in the treatment of parkinsonism and drug-induced extrapyramidal reactions.

biperiden

An ANTICHOLINERGIC drug used in the treatment of PARKINSON'S DISEASE. The drug is on the WHO official list. A brand name is Akineton.
References in periodicals archive ?
On February 27, 2018, the Moscow Arbitration Court declared lawful the decision of the Ministry of Health of the Russian Federation to abolish the state registration of the marginal sales prices of the drug Akineton (INN Biperiden, included in the list of VED), and the decision of the Federal Antimonopoly Service to cancel earlier adopted decisions of the Federal Tariff Service on the coordination of prices 1 .
His treatment included 30 mg/day aripiprazole, 1000 mg/day valproic acid, 200 mg/day quetiapine, 4 mg/day biperiden, and 100 mg/month paliperidone palmitate.
Martinez F, Forcen F, Shapov A, Martinez Moya A Biperiden dependence: case report and literature review.
With a suspected diagnosis of dystonia, biperiden lactate 5 mg/ml was administered via the intramuscular route and the contractions abated within 30 seconds of the injection.
Traditionally, benztiopine, biperiden, diphenhydramine, and trihexyphenidyl have been used for prevention and treatment of extrapyramidal side effects.
For example, changes in cholinergic transmission by drugs like scopolamine, metanicotine, biperiden and acetylcholinesterase inhibitors were reflected mainly in spectral delta power (Dimpfel 2005), whereas interaction with the noradrenergic alpha2 receptor could be traced within spectral theta frequencies (Dimpfel and Schober 2001).
This has been shown through many case reports, with at least partial response to anticholinergics (amitripryline, trihexyphenidyl, benztropine, biperiden, pirenzepine, ipratropium, scopolamine, hyoscine, atropine, and glycopyrrolate) and [alpha]-blockers (clonidine, lofexidine, guanfacine, and terazosin).
Valproic acid tabs 200, caps 150, 500 mg, syrup 300 mg 200 mg/5ml, Valproic acid caps 500 mg Anti-parkin- Biperiden inj.
Debido a esta ultima fue hospitalizada durante 30 dias y egreso con mejoria parcial;sin embargo, no se apego al tratamiento psicofarmacologico (trifluoperazina 20 mg/dia, carbamazepina 600 mg/dia, levomepromazina 25 mg/dia, biperiden 2 mg/dia)y un mes despues fue admitida nuevamente.