biosynthetic pathway


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pathway

 [path´wa]
a course usually followed. In neurology, the nerve structures through which a sensory impression is conducted to the cerebral cortex (afferent pathway), or through which an impulse passes from the brain to the skeletal musculature (efferent pathway). Also used alone to indicate a sequence of reactions that convert one biological material to another (metabolic pathway).
accessory pathway (accessory conduction pathway) extra muscle tissue between the atrium and ventricle that bypasses all or part of the normal conduction system. When the ventricles are activated prematurely via this pathway, initial forces are slow, producing the delta wave of wolff-parkinson-white syndrome, and preexcitation is said to exist; the delta wave causes the PR interval to shorten and the QRS interval to broaden.
alternative complement pathway see complement.
amphibolic pathway a group of metabolic reactions with a dual function, providing small metabolites for further catabolism to end products or for use as precursors in synthetic, anabolic reactions. The tricarboxylic acid cycle is an example. See also anabolism and catabolism.
biosynthetic pathway the sequence of enzymatic steps in the synthesis of a specific end-product in a living organism.
classical complement pathway see complement.
common pathway of coagulation the steps in the mechanism of coagulation (see clotting) from the activation of factor x through the conversion of fibrinogen to fibrin. See also intrinsic pathway of coagulation and extrinsic pathway of coagulation.
concealed accessory pathway an accessory pathway that has only retrograde conduction; thus its PR and QRS complexes are normal on the electrocardiogram, but there is a tendency to develop premature supraventricular tachycardia. If atrial fibrillation develops, conduction will proceed across the atrioventricular node.
Embden-Meyerhof pathway the series of enzymatic reactions in the anaerobic conversion of glucose to lactic acid, resulting in energy in the form of adenosine triphosphate (ATP).
extrinsic pathway of coagulation the mechanism that produces fibrin following tissue injury, beginning with formation of an activated complex between tissue factor and factor vii and leading to activation of factor x, which induces the reactions of the common pathway of coagulation. See also intrinsic pathway of coagulation.
final common pathway
1. the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.
2. any mechanism by which several independent effects exert a common influence.
intrinsic pathway of coagulation a sequence of reactions leading to fibrin formation, beginning with the contact activation of factor xii. This is followed by the sequential activation of factors xi and ix, which results in the activation of factor x. Activated factor X (factor Xa) initiates the common pathway of coagulation. See also extrinsic pathway of coagulation.
pentose phosphate pathway a pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final forming a pentose phosphate.

biosynthetic pathway

The chemical and metabolic events that lead to the formation of substances in the body.
See also: pathway

pathway

a course usually followed. In neurology, the nerve structures through which a sensory impression is conducted to the cerebral cortex (afferent pathway), or through which an impulse passes from the brain to the skeletal musculature (efferent pathway). Also used alone to indicate a sequence of reactions that convert one biological material to another (metabolic pathway).

biosynthetic pathway
the sequence of enzymatic steps in the synthesis of a specific end product in a living organism.
coagulation p's
see coagulation pathways.
Embden-Meyerhof pathway
final common pathway
1. the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.
2. any mechanism by which several independent effects ultimately exert a common influence.
pentose phosphate pathway
a pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, each producing NADPH, the final forming a pentose phosphate.
properdin pathway
alternative complement pathway.
References in periodicals archive ?
Based on different pathways involved in oxylipin biosynthesis, metabolites were classified by the main biosynthetic pathways COX, CYP, 5-LOX, and 12/15LOX (Figure 1; see also Table S4) (Zivkovic et al.
Gibson, "Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways," Journal of Lipid Research, vol.
In any case, the raising of PTPS activity provides a second mechanism by which sauna therapy raises BH4 synthesis, since lowering the degradative loss of neopterin triphosphate in the BH4 biosynthetic pathway will, of course, lead to increased biosynthesis of BH4.
The introduction of a novel branch pathway to a biosynthetic pathway represents one of the most useful approaches for increasing the level of metabolic diversity resulting from the pathway.
The production and activities of enzymes in the biosynthetic pathway are controlled by the mechasnism of feed back inhibition, repression and metabolic interlock due to which the wild strain can not accumulate lysine beyond its requirement.
Reduced root development in glyphosate-resistant soybean may be explained by the fact that the incorporation of the CP4-EPSPS gene in this plant species leads to drastic changes in the biosynthetic pathway of aromatic amino acids, reducing their levels (BRENBROOK, 2001).
More recently, the entire biosynthetic pathway for enterocin was reconstituted in vitro from recombinantly expressed enzymes (18).
The objective of the study is to clone and characterize one or more key polyketide synthase (PKS) genes associated with the production of solanapyrones in Ascochyta rabiei, to establish their role in the solanapyrone biosynthetic pathway and their effect on pathogenicity of the fungus.
In rice and in some other crops this can only be achieved using genetic engineering, because the biosynthetic pathway in the edible portions has been turned off as part of the plant's developmental program.
Thus, direct optimization of the rubber biosynthetic pathway seems to present the most likely route to achieve significant gains in latex and rubber yield.
Commonwealth Scientific & Industrial Research Organisation (Campbell, Australia), The Austrailian National University (Acton, Australia) and Biogemma SAS (Paris, France) have patente a nucleic acid sequence encoding an enzyme of the starch biosynthetic pathway in a cereal plant, wherein the enzyme is selected from the group consisting of starch branching enzyme I, starch branching enzyme II, starch soluble synthase I, and debranching enzyme, with the provisio that the enzyme is not soluble starch synthase I of rice, or starch branching enzyme I of rice or maize.