biological safety cabinet

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biological safety cabinet

A term for an enclosed and ventilated workspace in a microbiology lab, which is designed to contain pathogens. They are classified according to the protection they provide and the pathogens they are equipped to handle.

Types, biological safety cabinets 
Class I—provide protection for personnel and environment, but not the specimen itself. The airflow may be ducted externally or filtered and exhausted back into the laboratory.

Class II—provide protection for both personnel and equipment as well as the specimen. They are subdivided into 4 types: A1, A2, B1, B2, which are defined by National Science Foundation International Standard 49.

Class III—deployed only in maximum-containment laboratories and specifically designed for Biosafety Level 4 (Hazard Group 4 in the UK) pathogens, which include agents that cause Bolivian and Argentine haemorrhagic fevers, Marburg virus, Ebola virus, Lassa fever, Crimean-Congo haemorrhagic fever, smallpox, and other haemorrhagic diseases.
References in periodicals archive ?
Standard 49 was also updated to clarify that chlorine dioxide gas, when used for space decontamination of biosafety cabinets, should be generated outside of the biosafety cabinet and introduced to the sealed interior via a delivery system.
Personnel who process and perform laboratory testing on specimens from a PUI for EVD should wear gloves, fluid-resistant or impermeable gowns, full face shield or goggles, and masks to cover all of the nose and mouth AND use a certified Class II biosafety cabinet or Plexiglass splash guard.
They include (a) a real time PCR & thermocycler PCR system, (b) a double beam spectrophotometer, (c) a fluorescence microscope for so called Fish Technique, (d) an Elisa reader & washer, (e) an inverted microscope, (f) a light microscope with digital camera, (g) a DNA - RNA calculator, (h) cryogenic dewar flasks in 4 liters & 50 liters size, (i) a CO2 incubator with related accessories, (j) an autoclave, (k) a biosafety cabinet & (l) different type deep freezers.
BSL 4 * Work is done in a class III biosafety cabinet or in a biohazard suit that completely surrounds the worker.
The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet.
Co-workers reported that the patient had performed slide agglutination testing and recorded colonial morphology using typical biosafety level 2 (BSL 2) precautions; this did not entail the use of a biosafety cabinet.
Because the samples will be tiny, they may be best analyzed inside a small, closed compartment known as a biosafety cabinet, or glove box, says Race.
Tenders invited for Supply, safe delivery, installation, training and warranty of biosafety cabinet class ii type a2 as per annexure
Because the Axiom is an entirely new type of Class II biosafety cabinet, it can function in either Type A or Type B mode, saving money, time and energy in the process.
The CellGard ES NU-480 Class II Biosafety Cabinet features an exclusive TouchLink LCD Control Center, energy-saving DC-ECM motor, sloped window, and longer HEPA filter life.
6) All work with gram-negative or gram-variable small rods or coccobacilli isolated from tissues, blood, bone marrow, bone, or synovial fluid exudates should be carried out in a biosafety cabinet until Brucella has been ruled out.
Ranging from rabies to anthrax, moderately dangerous to lethal agents are studied in BSL-2 and BSL-3 labs, where all procedures must be conducted in a biosafety cabinet or other physically enclosed, HEPA-filtered (High Efficiency Particle Arresting) equipment.