biological safety cabinet

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biological safety cabinet

A term for an enclosed and ventilated workspace in a microbiology lab, which is designed to contain pathogens. They are classified according to the protection they provide and the pathogens they are equipped to handle.

Types, biological safety cabinets 
Class I—provide protection for personnel and environment, but not the specimen itself. The airflow may be ducted externally or filtered and exhausted back into the laboratory.

Class II—provide protection for both personnel and equipment as well as the specimen. They are subdivided into 4 types: A1, A2, B1, B2, which are defined by National Science Foundation International Standard 49.

Class III—deployed only in maximum-containment laboratories and specifically designed for Biosafety Level 4 (Hazard Group 4 in the UK) pathogens, which include agents that cause Bolivian and Argentine haemorrhagic fevers, Marburg virus, Ebola virus, Lassa fever, Crimean-Congo haemorrhagic fever, smallpox, and other haemorrhagic diseases.
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Personnel who process and perform laboratory testing on specimens from a PUI for EVD should wear gloves, fluid-resistant or impermeable gowns, full face shield or goggles, and masks to cover all of the nose and mouth AND use a certified Class II biosafety cabinet or Plexiglass splash guard.
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The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet.
Because the samples will be tiny, they may be best analyzed inside a small, closed compartment known as a biosafety cabinet, or glove box, says Race.
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LabGard ES NU-540 Biosafety Cabinet Construction Highlight
6) All work with gram-negative or gram-variable small rods or coccobacilli isolated from tissues, blood, bone marrow, bone, or synovial fluid exudates should be carried out in a biosafety cabinet until Brucella has been ruled out.
If tularemia is suspected, the plates must be sealed and opened only in a biosafety cabinet using BSL 3 precautions.
The CellGard ES NU-480 Class II Biosafety Cabinet features an exclusive TouchLink LCD Control Center, energy-saving DC-ECM motor, sloped window, and longer HEPA filter life.
Subculturing and biochemical tests were conducted in a class II biosafety cabinet.