biological readout

biological readout

A term of art referring to the result of a molecular interaction or gene activation—e.g., hair depigmentation as a readout for pharmacologic inhibition of the KIT receptor tyrosine kinase.
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The SOLiD challenge is to sequence both the genome and the RNA content of a single cancer cell, effectively doubling the biological readout that is currently achievable by sequencing a single cell.
Cadus' human cell-based assays make use of biological readouts involving the MEK Kinase pathways.
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