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biologic plausibility

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biologic plausibility,
a method of reasoning used to establish a cause-and-effect relationship between a biologic factor and a particular disease.


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The same severe fixed obstructive syndrome in many flavoring manufacturing workers (3, 4) substantiates the hazard of diacetyl, and biologic plausibility now exists in rodent toxicology studies (5-7).
We prefer to perform conventional statistical tests, without Bonferroni correction, and look at the pattern of significant effects and their biologic plausibility.
2,3) The biologic plausibility is also strong, because ephedra is known to contain ephedrine and other sympathomimetic agents that increase heart rate, blood pressure, cardiac contractile force, and vasoconstriction.
 
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