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biologic half-life

   Also found in: Dictionary/thesaurus, Financial, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
biologic half-life,
the time required for the body to eliminate half of an administered dose of any substance by regular physiologic processes. The biologic half-life is approximately the same for stable and radioactive isotopes of a specific element. Also called metabolic half-life. See also effective half-life, half-life.

half-life,
n the time in which a radioactive substance will lose half of its activity through disintegration.
half-life, biologic,
n the time in which a living tissue, organ, or individual eliminates, through biologic processes, half of a given amount of a substance that has been introduced into it.
half-life, effective,
n the half-life of a radioactive isotope in a biologic organism, resulting from the combination of radioactive decay and biologic elimination.
half-life, physical,
n the average time required for the decay of half the atoms in a given amount of a radioactive substance.


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1) Triamcinolone acetonide is considered an intermediate-acting steroid with a biologic half-life of 18 to 36 hours (2) and is available in suspension form, which provides an increased duration of action.
It also indicates that to make the evaluation possible, the dietary exposures on the dietary-exposed day also need to be large; the biologic half-life of the chemical, [T.
In this study, co-administration of Defibrotide with heparin produced an augmentation of the effect of heparin and an increase in the biologic half-life.
 
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