biologic half-life


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bi·o·log·ic half-life

the time required for one-half of an amount of a substance to be lost through biologic processes.

biologic half-life,

the time required for the body to eliminate half of an administered dose of any substance by regular physiologic processes. The biologic half-life is approximately the same for stable and radioactive isotopes of a specific element. Also called metabolic half-life. See also effective half-life, half-life.

bi·o·log·ic half-life

(bī'ŏ-loj'ik haf'līf)
The time required for one half of an amount of a substance to be lost through biologic processes.

bi·o·log·ic half-life

(bī'ŏ-loj'ik haf'līf)
The time required for one half of an amount of a substance to be lost through biologic processes.
References in periodicals archive ?
Results of variations in the surface loading and urinary metabolites for a compound with a biologic half-life of 8 hr are shown in Figure 4.
Based upon a pesticide with a biologic half-life of 8 hr and assuming a variance of 2 due to measurement errors, a minimum sample size of five pairs of the exposed day and the nonexposed day would be required in homes with pesticide loading [greater than or equal to] 4 ng/[cm.
The single-compartment model may not be as accurate as a multicompartment PK model in prediction, but it has a practical advantage--only two parameters are essential to build a model: the biologic half-life of the chemical and the proportion of the chemical eliminated in overnight void.