biologic activity

biologic activity,

the inherent capacity of a substance, such as a drug or toxin, to alter one or more chemical or physiologic functions of a cell, tissue, organ, or organism. The biologic activity of a substance is determined not only by the substance's physical and chemical nature but also by its concentration and the duration of cellular exposure to it. Biologic activity may reflect a "domino effect," in which the alteration of one function disrupts the normal activity of one or more other functions.
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BAY 94-9027 has been designed to extend the circulating half-life of rFVIII activity through site specific attachment of a polyethylene glycol (PEG) polymer to the light chain of the rFVIII molecule, while preserving its full biologic activity.
BAY94-9027 has been designed to extend the circulating half-life of rFVIII through site specific attachment of a polyethylene glycol (PEG) polymer to the light chain of the rFVIII molecule, while preserving its full biologic activity.
It's also possible that some unknown biologic activity could be at play.
It's also questionable whether the biologic activity of this source of hyaluronic acid compares with the others.
In the Phase 1 trial launched in India, a total of 84 healthy volunteers will receive various doses of the new MAB to test the tolerability and biologic activity of the MAB in people.
Since metabolic processes that take place in cells produce isotopically light carbon, a high concentration of carbon-12 is often a sign that the carbon was generated by biologic activity, Whitehouse adds.
A much-higher-than-average concentration of carbon-12, the lightest of carbon's stable isotopes, often is a sign that the carbon was generated by biologic activity, says Whitehouse.
As macroprolactin does not have biologic activity, such patients do not require further investigations or treatment for hyperprolactinemia.
Several adverse health effects, such as respiratory and cardiovascular morbidity, have been linked to exposure to particulate matter in ambient air; however, the biologic activity of gas-phase ambient organic air contaminants has not been examined as thoroughly.
A comparison of the biologic activity of two recombinant IFN-beta preparations used in the treatment of relapsing-remitting multiple sclerosis.
According to the company, in a recent clinical trial, Respondin demonstrated biologic activity in elevating antibody levels associated with the influenza vaccine.
The primary objectives of the study are to evaluate the tumor response rate and response duration as well as to evaluate the biologic activity of Metastat by measuring serum levels of pro-angiogenic mediators.