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biologic activity

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biologic activity,
the inherent capacity of a substance, such as a drug or toxin, to alter one or more chemical or physiologic functions of a cell, tissue, organ, or organism. The biologic activity of a substance is determined not only by the substance's physical and chemical nature but also by its concentration and the duration of cellular exposure to it. Biologic activity may reflect a "domino effect," in which the alteration of one function disrupts the normal activity of one or more other functions.


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Glucocorticoids are drugs that have biologic activity similar to the hormones made in the adrenal glands.
According to the company, in a recent clinical trial, Respondin demonstrated biologic activity in elevating antibody levels associated with the influenza vaccine.
Functional assays, which can measure the biologic activity of a compound or mixture of compounds, have the potential to provide valid and relevant exposure assessments.
 
 
 
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