biohybrid organ

biohybrid organ

A device which marries biologic units—e.g., cells or tissues—to a delivery vehicle to immunoisolate the units from a host immune response.

Trialed designs
Perfusion shunts, diffusion chambers, microspheres, polymer membranes.

biohybrid organ

Therapeutics A device that marries biologic units–eg, cells or tissues, to a delivery vehicle to circumvent–through immunoisolation–immune attack on transplanted–non-self tissues. See Artificial liver, Artificial pancreas, Bioengineering.
References in periodicals archive ?
Most helpful would be an artificial or bioartificial liver assist device that could be used to sustain patients and serve as a bridge to liver transplantation, which is the only effective treatment that is currently available for fulminant for the university's leading scientists and clinical faculty working to develop tissue engineering, cellular therapies, and artificial and biohybrid organ devices.
Professor of Surgery and of Bioengineering at the McGowan Institute -- Recruited from Humboldt University, Berlin; one of the world's leading biohybrid organ designers who is developing a bioartificial liver to sustain patients going through the healing process or waiting for a transplant.
Among the investigators working in the BST3 facility will be some members of the McGowan Institute for Regenerative Medicine, which serves as a base of operation for the University's scientists and clinical faculty whose research focuses on developing tissue engineering, cellular therapies, biosurgery and artificial and biohybrid organs.