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biogenic amine |
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amine (ah-mēn´) (am´in) an organic compound containing nitrogen; any of a group of compounds formed from ammonia by replacement of one or more hydrogen atoms by organic radicals. biogenic amine a type of amine synthesized by plants and animals and frequently involved in signaling, e.g., neurotransmitters such as acetylcholine, catecholamines, and serotonin; others are hormones or components of vitamins, phospholipids, bacteria, or ribosomes, e.g., cadaverine, choline, histamine, and spermine. sympathomimetic amines amines that mimic the actions of the sympathetic nervous system, comprising the catecholamines and drugs that mimic their actions.
biogenic amine, one of a large group of naturally occurring biologically active compounds, most of which act as neurotransmitters. The most dominant, norepinephrine, is involved in such physiologic functions as emotional reactions, memory, sleep, and arousal from sleep. Other biochemicals of the group include three catecholamines: histamine, serotonin, and dopamine. These substances are active in regulating blood pressure, elimination, body temperature, and many other centrally mediated body functions. biogenic having the property of originating in a biological process. biogenic amine an amine neurotransmitter, such as epinephrine, norepinephrine, serotonin or dopamine. endogenous biogenic amines occur naturally in the body, e.g. epinephrine, norepinephrine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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These correlations, which indicate an increased dopamine metabolism, agree with recent experimental data in rats, showing that cadmium interferes with biogenic amine release from the hypothalamus, thereby inhibiting prolactin secretion (Lafuente et al. Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis. Indeed, Rosin and Martin (1981) reported significant reductions in uptake of biogenic amine neurotransmitters into synaptosomes after exposure to Aroclor mixtures, whereas Mariussen and Fonnum (2001) recently reported that only noncoplanar PCB congeners inhibited uptake of labeled DA into striatal synaptosomes. |
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