binding site


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Related to binding site: Ribosome binding site, substrate binding site

binding site

Etymology: ME, binden + L, situs
the location on the surface of a cell or a molecule where other cell fragments or molecules attach to initiate a chemical or physiological action.

binding site

(1) Antigen-binding site, see there.
(2) A nonspecific term for any site at which two or more molecules join as a part of a reaction.

binding site

an area of an ENZYME to which other molecules can attach. Such an area can be an ACTIVE SITE for particular substrates or for other molecules, as in COMPETITIVE INHIBITION. Alternatively, some enzymes possess two binding sites, one for substrate attachment, the other for attachment of other molecules as in noncompetitive inhibition and allosteric inhibition (see ALLOSTERIC INHIBITORS).

binding site,

n the location on the surface of a cell or molecule where other cell fragments or molecules attach to initiate a chemical or physiologic action.

Patient discussion about binding site

Q. My friend has Progressive MS, he is bound to a wheelchair, Prognosis? How can I help? He must be moved by a Hoyer Lift, he has caregivers. He has a beautiful voice and does have enough ability to move in his chair around local community. He has some bad days with spacicity, I want to help but am unsure as to how? He is 60? or so and lives on his own, he has had MS for many years and a number of complications, such as pneumonia and decubitus. Please help me to help him!

A. There are a number of ideas and resources for social and recreational activities (i.e. wheelchair sports, dancing, travel, aviation, etc.) that may be helpful, which can be found at www.mobility-advisor.com.

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References in periodicals archive ?
Furthermore, C8[beta] effectively blocks C8 incorporation into the MAC; therefore it must compete for the same binding site on C5b-7.
Gilliland, Location of a Potential Transport Binding Site in a Sigma Class Glutathione Transferase by X-ray Crystallography, Proc.
Double celebration: The Binding Site board, from left, Hugh Carr-Smith, production director, Trevor Sykes, company secretary and group finance director, Charles de Rohan, chief executive, Paul Duncan, sales director, Mark Culwick, CFO and Graham Mead, research and development director.
With extensive expertise in antibody specificity technology, Binding Site gives clinicians and laboratory staff tools to improve diagnosis and management of patients across a range of B-cell cancers and immune system disorders.
The Binding Site is Cure Leukaemia's first charity partner to introduce payroll donations, a method many employees have already signed up to.
The researchers showed that the number of evolutionary adaptations to the part of the machinery that regulates genes, called transcription factor binding sites, might be roughly equal to adaptations to the genes themselves.
Freelite is a unique assay, developed and marketed by The Binding Site, used for the diagnosis and monitoring of multiple myeloma (MM) and related disorders.
On human chromosome 2, RUNX1 fits into a binding site that lies in the middle of a gene called programmed cell death 1, or PDCD1.
STAFF from chartered accountants Clement Keys abseiled down their building, The Binding Site, to raise money for St Edward's Trust as part of a family fun day.
The Binding Site Limited ("The Binding Site" or the "Company"), a privately-owned specialist UK diagnostics company, today announces a trading update for the year ended 30th September 2008.
However, Koning says, finding an effective inhibitor for DQ2 may take time because its binding site doesn't grab onto molecules as tightly as the tTGase binding site does.