binding domain

binding domain

Any structural motif present on a DNA-binding regulatory protein which controls gene expression, either enhancing or repressing mRNA synthesis. Binding proteins recognise sequence-specific binding domains on DNA and often share sequence homology with each other—e.g., leucine zipper motif and protein products of the myc, fos, and jun proto-oncogenes.
References in periodicals archive ?
To create this novel hydrogel, the team assembled genetically-engineered proteins into molecular networks by stitching together the photoreceptor C-terminal adenosylcobalamin binding domain (CarHC) proteins at room temperature.
InterProScan and MOTIFSCAN tools were used to locate and analyze conserve DNA binding domain.
soloMERs are the smallest (9% of the size of an antibody) and most robust naturally occurring binding domain which makes them ideal for binding to intracellular targets.
The replacement of W357 of loop 1 in binding domain of Cry19Aa with alanine resulted in the loss of toxicity against mosquitoes.
Amino acid diversity within the HMW binding domain likely serves the diversity of hmwA locus in various strains (14).
E7777 is a fusion protein that combines the interleukin-2 (IL-2) receptor binding domain with diphtheria toxin fragments.
E7777 is a fusion protein that combines the interleukin-2 receptor binding domain with diphtheria toxin fragments.
They discuss structural characterization of EPAC by x-ray crystallography; sensory neuron cAMP signaling in chronic pain; monitoring real-time cyclic nucleotide dynamics in subcellular microdomains; identifying complexes of adenylyl with A-kinase anchoring proteins; assessing cyclic nucleotide binding domain allostery and dynamics by nuclear magnetic resonance spectroscopy; a protocol for expression and purification of cyclic nucleotide-free protein in E.
Atypical VWF function can be a result of missing VWF multimers (type 2A, type 2B, and platelet-type) or loss-of-function mutations in the platelet binding domain (type 2M) or factor VIII binding domain (type 2N) of VWF.
About TALEN technology Transcription activator-like effector nucleases (TALENs) are artificial restriction enzymes generated by fusing a TAL effector DNA binding domain to a DNA cleavage domain.
Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase CD1 [74].