biliary brushing

biliary brushing

A cytology technique of waning popularity for diagnosing cancer of the biliary, in which a brush is introduced endoscopically and the cells obtained are assessed by light microscopy.
 
While biliary brushing has a high specificity (up to 100%), its specificity can also be as low as 30%; the false-negativity is due to sampling error, size and location of lesion, fibrosis, technical errors, interpretive difficulties related to specimen inadequacy, admixed benign elements, necrosis, lack of familiarity with dysplastic lesions, well-differentiated carcinoma and rare tumours. Liquid-based cytology is increasingly preferred.
References in periodicals archive ?
Other authors (9,10) have found that when only polysomic results were considered in biliary brushing or washing specimens, the specificity was 100%.
Trisomy has been correlated with malignancy in urine samples and biliary brushing or washing (BBW) specimens in some investigations.
Other studies (12-14) have reported the utility and value of UFISH primarily in biliary brushings.
Improving diagnostic yield of biliary brushings cytology for pancreatic cancer and cholangiocarcinoma.