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Effect of pravastatin, an HMG CoA reductase inhibitor, and cholestyramine, a bile acid sequestrant, on lipoprotein particles defined by their apolipoprotein composition.
9,23) Bile acid sequestrants would be the second choice for treatment of patients with isolated elevated cholesterol.
WelChol is the top-selling branded drug in the bile acid sequestrants (BAS) class.
Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compounds (HMG-CoA reductase inhibitors, bile acid sequestrants (resins), fibric acid derivatives, and plant stanols).
WelChol, a non-absorbed specifically engineered bile acid sequestrant (SE-BAS) indicated for LDL-C lowering approved by the U.
Combining a bile acid sequestrant to provide additional LDL-cholesterol-lowering with a fenofibrate to lower triglyceride levels may provide an alternate therapy which can positively affect lipid levels.
The findings were consistent across two different dosing options of the two cholesterol-lowering therapies -- when WelChol, a bile acid sequestrant (BAS), was given at the same time as TriCor, a fibrate, or when TriCor was given four hours prior to WelChol.
Other major lipid-modulating drugs, such as Zetia (ezetimibe), the fibrates, bile acid sequestrants, omega-3 fish oil agents, and rare-disease therapies comprise the remainder of the current dyslipidemia space.
To calculate the market size, the Global Type 2 Diabetes Therapeutics Market 2015-2019 report considers revenue generated through the sales of drugs like DPP-4 inhibitors, Biguanides, Insulins, GLP-1 receptor agonists, Thiazolidenediones, Sulfonulureas, SGLT-2 inhibitors, a-Glucosidase inhibitors and others (amylinomimetics, bile acid sequestrants, and dopamine receptor agonists).
Certain medications, including estrogens, bile acid sequestrants, and protease inhibitors, can raise triglyceride levels.
They are largely derived from wood pulp and decrease the absorption of cholesterol across the gut wall by a mechanism separate from ezetimibe or the bile acid sequestrants.
The therapy chapters include discussion of such topics as treatment guidelines, exercise and lipids, weight loss, statins, bile acid sequestrants, cholesterol absorption inhibitors, nicotinic acid, fibrates, endocannabinoid receptor blockers, modulation of biomarkers of inflammation, invasive imaging modalities and atherosclerosis, and noninvasive imaging modalities.