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biguanides |
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biguanides (bīgwan´īdz), n.pl orally administered agents used in the treatment of type 2 diabetes, which prevents the liver from breaking down glycogen into glucose and increases the sensitivity body tissues have to insulin. See metformin HCl. biguanides a class of disinfectants, the most common one being chlorhexidine. |
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Of the three primary categories of oral agents--secretagogues, biguanides, and thiazolidinediones--none have been systematically studied during the perioperative period. A common cause is long-term usage of biguanides (metformin) and antacids, including H2-receptor antagonists and proton pump inhibitors. He notes there are several medications on the market to help control Type II diabetes, such as sulfonylureas, which help the pancreas produce more insulin; biguanides, which lessens the amount of glucose the liver produces; and thiazolidinediones, which helps make blood cells more receptive to insulin. |
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biguanides