tubulin

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tubulin

 [too´bu-lin]
the constituent protein of microtubules; thought to be involved in phagocyte motility.

tu·bu·lin

(tū'byū-lin),
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein.

tubulin

/tu·bu·lin/ (too´bu-lin) the constituent protein of microtubules.

tubulin

(to͞o′byə-lĭn, tyo͞o′-)
n.
A globular protein that is the basic structural constituent of microtubules.

tu·bu·lin

(tū'byū-lin)
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein

tubulin

A contractile protein that forms microtubules. These form the spindle fibres in MITOSIS that draw chromosomes apart is the course of cell division.

tubulin

a globular protein molecule, similar to ACTIN, that is the building block of microtubules within the cytoplasm of cells.

tubulin

the constituent protein of microtubules of cells which provide a skeleton for maintaining cell shape and is thought to be involved in cell motility.

α-tubulin
with β-tubulins contributes to the heterodimer tubulin, the building blocks of the electron microscopically visible cell components, the microtubules.
β-tubulin
one of the monomeric globular proteins which associate to form the dimer, α,β-tubulin, the basis of microfilaments.
References in periodicals archive ?
Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in beta-tubulin isotype 1.
Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans.
Importance of the mutation of amino acid 200 of the isotype l beta-tubulin gene in the benzimidazole resistance of the small-ruminant parasite Teladorsagia circumcincta.
Allele-specific PCR for the beta-tubulin codon 200 TTC/TAC polymorphism using single adult and larval small strongyle (Cyathostominae) stages.
Detection of codon for amino acid 200 in isotype 1 beta-tubulin gene of Wuchereria bancrofti isolates, implicated in resistance to benzimidazoles in other nematodes.
Sequence variation in the Trichuris trichiura beta-tubulin locus: implications for the development of benzimidazole resistance.
The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.
Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients.
Alterations of beta-tubulin isotypes in breast cancer cells resistant to docetaxel.
Differential localization of class III, beta-tubulin isotype and calbindin-D28k defines distinct neuronal types in the developing human cerebellar cortex.
Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology.
Expression of class III beta-tubulin in neuroendocrine tumours of gastrointestinal tract.