beta-receptor


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beta-receptor

(bā′tə-rĭ-sĕp′tər, bē′-)
n.
A site in the autonomic nervous system in which inhibitory responses occur when adrenergic agents, such as norepinephrine and epinephrine, are released. Activation of beta-receptors causes various physiological reactions, such as relaxation of the bronchial muscles and an increase in the rate and force of cardiac contraction. Also called beta-adrenergic receptor.
References in periodicals archive ?
It showed that blocking the beta-receptor alone promotes cardiac remodelling via growth of cardiac fibroblasts induced by alpha-adrenergic receptor signaling.
Beta-blockers that target both the alpha- and beta-receptors on the heart muscle offer the most benefit to cardiac patients, while those that target only the beta-receptors can actually undermine the structure and function of the heart.
We also expect to bring three new programs into the clinic next year: ADENTRI(TM) for acute and chronic congestive heart failure, LT beta-receptor for autoimmune diseases, and interferon beta gene therapy for glioma.
It also could change treatment programs, perhaps by incorporating the monitoring of a patient's ratio of alpha- to beta-receptor stimulation or by developing medications that act on receptor sites.
Inverseon has been taking an opposite approach in the chronic treatment of asthma by using 'inverse agonists' or blockers, instead of agonists or stimulants, of the beta-receptor.
CDP 860 (PEGylated Anti-PDGF beta-receptor antibody fragment) is a PEGylated humanized antibody fragment that specifically binds to and blocks the beta receptor for Platelet Derived Growth Factor (PDGF).
Beta-blockers, like carvedilol, metoprolol, bisoprolol and nebivolol, block the beta-receptors on heart cells, which when stimulated make the heart rate increase.
2] Increased tone and frequency of contractions are believed to result from stimulation of alpha-receptors, and reduced activity from stimulation of beta-receptors.
Noradrenaline, released from sympathetic nerve endings, acts on beta-receptors in the myocardium to increase the rate of contraction.
CS in turn have a positive effect on beta-receptors.
Increased tone and frequency of contractions are believed to result from stimulation of beta-receptors, and reduced activity from stimulation of alpha-receptors.