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beta-lactam

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lactam /lac·tam/ (lak´tam) a cyclic amide formed from aminocarboxylic acids by elimination of water; lactams are isomeric with lactims, which are enol forms of lactams.
β-lactam  see under antibiotic.

beta-lactam
n.
Any of a class of broad-spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins.


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As there have been bacteriologically documented failures in patients infected with pneumococci when the MIC is over 8 mg/L [65], in regions with a high rate (> 25 %) of infection with high-level (MIC = 16 mg/L) macrolide-resistant pneumococci, using of alternative agents like respiratory fluoroquinolones (moxifloxacin, gemifloxacin, levofloxacin) or a beta-lactam plus a macrolide is recommended in outpatient CAP [13].
One of the drugs they studied, clavulanate, inhibits the bacterial enzyme beta-lactamase, which usually protects tuberculosis bacteria from the other antibiotic, meropenem, which comes from the beta-lactam class of antibiotics.
Interim controls for the containment of beta-lactam antibiotics such as penicillins, cephalosporins and penems were inadequate, the investigators found.
 
 
 
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