beta thalassemia


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Related to beta thalassemia: Alpha Thalassemia

β thal·as·se·mi·a

thalassemia due to one of two or more genes that depress (partially or completely) synthesis of β-globin chains by the chromosome bearing the abnormal gene. Heterozygous state (A2 t.): thalassemia minor with Hb A2 increased, Hb F normal or variably increased, Hb A normal or slightly reduced. Homozygous state: thalassemia major with Hb A reduced to very low but variable levels, Hb F very high level.
References in periodicals archive ?
Table I: Prevalence of disease carriage in both sexes Male Female Total n % n % n % Beta Thalassemia trait 5709 6.
In addition, beta thalassemia and alpha thalassemia are very prevalent in the population.
Genetically modifying male sperm in the population to wipe out the gene that causes beta thalassemia could get rid of the disease.
Myelodysplastic syndromes (MDS), beta thalassemia, and sickle cell disease (SCD) are examples of these types of disorders and are associated with moderate to severe anemia.
The statistics also showed that 193 are beta thalassemia carriers and 118 people had sickle cell trait.
Carrier testing for beta thalassemia is more complicated and the interpretation more nuanced.
The distribution and incidence of beta thalassemia genes in different populations.
A hereditary defect in synthesis of a crucial blood protein in mice, which constitutes a disease similar to beta thalassemia in humans, has been corrected by the transfer of the corresponding human gene into mouse reproductive cells.
The Company will evaluate these novel peptides as potential therapeutics for the treatment of beta thalassemia and other diseases associated with iron overload.
Funds Will Support Research Into Safety and Efficacy of Umbilical Cord Stem Cell Transplantations to treat Beta Thalassemia Major
Intermedia is a beta thalassemia group characterized by severity varying from thalassemia major to asymptomatic carriers.