beta thalassemia

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Related to beta thalassemia: Alpha Thalassemia

β thal·as·se·mi·a

thalassemia due to one of two or more genes that depress (partially or completely) synthesis of β-globin chains by the chromosome bearing the abnormal gene. Heterozygous state (A2 t.): thalassemia minor with Hb A2 increased, Hb F normal or variably increased, Hb A normal or slightly reduced. Homozygous state: thalassemia major with Hb A reduced to very low but variable levels, Hb F very high level.
References in periodicals archive ?
When laboratory features are discordant for a diagnosis of beta thalassemia trait, it is useful to consider other conditions that affect the Hb [A.
2,3 To date, rheumatological complications such as arthritis, arthropathies, joint effusions, osteoporosis, bone fractures, connective tissue disorders, pseudoxanthoma elasticum and myalgias have been defined in beta thalassemia.
It should be noted that in some of the reported studies, comparing is performed between alpha-beta thalassemia with normal cases or in more than two groups but our emphasis was comparison between beta thalassemia carriers with alpha- beta thalassemia carriers in hematology indices so increasing amounts occur in very small scales (8,45).
Coexistent iron deficiency was seen in 51% of beta thalassemia patients.
Endocrine complications in patients of beta thalassemia major in a tertiary care hospital in Pakistan.
A total of 300 patients with confirmed diagnosis of beta thalassemia major reported to Pediatric OPD during the study period.
Comparison of a transfusion preparation of newly formed red cells and standard washed red cell transfusion in patients with homozygous beta thalassemia.
Bimaxillary hyperplasia; The facial expression of homozygous Beta thalassemia.
Beta thalassemia carrier detection by NESTROFT: an answer in rural scenario.
Low serum calcium is very prevalent in transfusion-dependant beta thalassemia major patients in our set up possibly due to poor chelation as was confirmed by our study where 49% of patients had hypocalcemia.
Beta thalassemia and sickle cell disease are genetic diseases of blood cells that can cause life-threatening anaemia and often require frequent and life-long blood transfusions.