beta receptor


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Related to beta receptor: alpha receptor

beta receptor

any one of the postulated adrenergic (sympathetic fibers of autonomic nervous system) components of receptor tissues that respond to epinephrine and such blocking agents as propranolol. Activation of beta receptors causes various physiological reactions such as relaxation of the bronchial muscles and an increase in the rate and force of cardiac contraction. Also called beta-adrenergic receptor. Compare alpha receptor.

beta receptor

A trio of G protein-coupled cell membrane receptors in the sympathetic nervous system, which dampen the response to catecholamines. They are divided into Beta-1, -2 and -3 receptors.

Beta-1 receptor increases cardiac output by raising the heart rate, impulse conduction, and contraction, thereby increasing the left ventricular ejection fraction; increases juxtaglomerular renin secretion; increases gastric secretion of ghrelin (the hunger hormone, which contrasts to leptin, the satiation hormone).

Beta-2 receptor prompts smooth muscle relaxation resulting in bronchodilation; reduced GI motility; relaxation of detrusor muscle of the bladder; glycogenolysis and gluconeogenesis; and increased renin secretion.

Beta-3 receptor increases lipolysis in fat and thermogenesis in skeletal muscle.
References in periodicals archive ?
Bonnie Deroo, of the University of Western Ontario, in London (Canada), studies one impact of the missing beta receptor in female mice--fertility problems.
Corticosteroids can reverse the desensitization of beta receptors and are said to be able to potentiate the response to beta agonists.
Working with Rigel and having access to their TGF beta receptor kinase inhibitors extends our existing portfolio of immunotherapeutic approaches to include this key mediator of immunosuppression in the tumor microenvironment.
Probably, drug with effect on alpha and beta receptors and change in kidney tissue causes changes of kidney morphometric and changes in secretion of kidney factors.
Scottish pharmacologist James Black working for ICI Pharmaceuticals in Britain took on the challenge of constructing molecules that would preferentially block beta receptors.
The fat level of our body is controlled by sets of cells called alpha and beta receptors.
Data from displacement binding assays using recombinant estrogen alpha and beta receptors will be presented.
They 'block' beta receptors - sites on body tissues where chemicals released from nerve endings bind and increase the force and speed of the heart beat.
Prof Risbridger said: "The team at Monash University has discovered how this compound working through the beta receptors targets a small, but very important, population of cells in the tumour.
In contrast, Boue notes, daidzein and genistein have their biggest effect on the beta receptors.
Glucocorticoids enhance beta-receptor stimulation by increasing the number and availability of beta receptors on the cell surfaces and by increasing affinity of the receptor for beta agonists.