benzonatate


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benzonatate

 [ben-zo´nah-tāt]
an antitussive that depresses cough without affecting respiration, by anesthetizing stretch receptors in the respiratory passages, lungs, and pleura. It is administered orally in capsule or tablet form, but should not be chewed or dissolved in the mouth because the local anesthetic action may cause numbness of the oral mucosa.

ben·zo·na·tate

(ben-zō'nă-tāt),
An antitussive agent related chemically to tetracaine; thought to act by depressing mechanoreceptors in the lungs.

benzonatate

/ben·zo·na·tate/ (ben-zo´nah-tāt) an antitussive that reduces the cough reflex by anesthetizing the stretch receptors in the respiratory passages, lungs, and pleura.

benzonatate

[benzō′nətāt]
a nonopiate antitussive.
indication It is prescribed to suppress the cough reflex.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Hypersensitivity reactions, such as bronchospasm, laryngospasm, and cardiovascular collapse, may occur and may be serious. Vertigo, sedation, headache, and constipation may sometimes occur.

ben·zo·na·tate

(ben-zō'nă-tāt)
Antitussive related chemically to tetracaine.

benzonatate (benzon´ətāt´),

n brand name: Tessalon;
drug class: antitussive, nonnarcotic;
action: inhibits cough reflex by anesthetizing stretch receptors in respiratory system;
uses: nonproductive cough relief.

benzonatate

a non-narcotic antitussive drug that depresses cough without affecting respiration.
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References in periodicals archive ?
Our proprietary technology allows us to bind benzonatate to a resin particle, which represents a completely novel formulation approach and resolves this significant safety issue.
Howard added: "This Notice of Allowance marks an important milestone in our benzonatate product development strategy and may be the key to benzonatate becoming a successful Rx-to-OTC switch candidate.
In the past, patients would receive 2 100-mg benzonatate perles, which they kept on the tongue until the perles dissolved.
9 ml * Benzocaine/tetracaine spray 2-sec spray Benzonatate 200 mg * When tetracaine is administered via an atomizer for nasal anesthesia, only 0.
Our oral-solid ion exchange resin benzonatate formulation has been shown to reduce or eliminate the choking hazard associated with this effective non-narcotic cough suppressant," said Alitair President and CEO, William W.
Overcoming this significant safety hurdle may be the key to benzonatate becoming a successful Rx-to-OTC switch candidate," continued Howard.
Alitair has filed an additional patent related to its benzonatate product candidate to further strengthen the Company's intellectual property portfolio.
Alitair is filing a second patent related to its benzonatate product candidate, which will further strengthen the Company's intellectual property portfolio.
A review of the FDA's Adverse Event Reporting System database from 1982 through May 2010 identified seven cases of accidental ingestion associated with benzonatate in children younger than 10.
The FDA is also adding a new Warning and Precaution section to the benzonatate drug label to warn health care professionals about accidental ingestion resulting in overdose and death in children younger than 10.