4 million units of long-acting
benzathine penicillin G.
Benzathine penicillin G is used in many countries but is unavailable in others, such as Japan.
Advice to health professionals: Use of lignocaine as a diluent to reduce the pain associated with the administration of
benzathine penicillin G.
Contract awarded for code: 29
benzathine penicillin g powder for parenteral use 1 200,000 iu vial
Benzathine penicillin G is the only known effective treatment for preventing CS (3).
Use of
Benzathine penicillin G, (42000 IU/kg, weekly intervals for 3 weeks), Benzathine and procaine penicillin (42 000-84 000 IU/kg, weekly intervals for 3 weeks) has been reported to cure the condition by Cynthia (2005) and David (2012).
Recommended antimicrobial agents in those who have group A streptococcus include penicillin V, amoxicillin, or intramuscular
benzathine penicillin G in those without penicillin allergy and cephalexin/cefadroxil, clindamycin, or azithromycin/clarithromycin in those who do have penicillin allergy.
2) One of the major disadvantages of IM injection of penicillins, such as
benzathine penicillin G, is pain at the injection site.
Compared with treating HIV infection, or even gonorrhea, treating syphilis remains blessedly simple--and cheap: Two shots of
benzathine penicillin G and you're good to go, even if you have HIV infection (usually).
The Centers for Disease Control and Prevention's new treatment guidelines for STDs recommend
benzathine penicillin G 2.
If compliance is a problem, intramuscular
benzathine penicillin G is recommended.
If the doctor has concerns that the child will receive all the medicine, then one injection of
benzathine penicillin G may be the best treatment.