benzamide


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Related to benzamide: benzanilide

benzamide

A crystal obtained by the action of ammonia on benzoyl chloride. Chemical derivatives of benzamide are used in a wide range of therapeutics including analgesics (e.g., salicylamide), antiemetics (e.g., metoclopramide), antipsychotics (e.g., sultopride) and other agents.

benzamide

(ben-zam′īd″) [ benzoin + amide]
Any of a class of drugs, including domperidone, metoclopramide, and trimethobenzamide, that block dopamine and serotonin receptors and stimulate acetylcholine receptors in smooth muscle. They are principally used to treat nausea and vomiting.
References in periodicals archive ?
We are pleased to collaborate with Active Biotech to further advance the development of the benzamide technology within the field of inflammatory diseases," said Bjorn Nordenvall, Ph.
Topical repellents constitute a wide array of chemicals ranging from natural botanicals such as citronella to synthetically derived N,N-Diethyl-3-methyl benzamide (deet).
5 wt% triglycidyl isocyanurate in the presence of catalytically acting amines or salts [28], and a variety of N,N-diglycidyl substituted benzamide, aniline, diimide or imidazolone compounds [29].
Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs.
About HBI-8000 (chidamide) HBI-8000 (chidamide) is a member of the benzamide class of histone deacetylase (HDAC) inhibitors designed to block the catalytic pocket of Class I HDACs.
In the area of vector-borne disease prevention, personal protective equipment consisting of use of topical insect repellent, N, N-diethyl-3-methyl benzamide (deet) and proper wear of permethrin treated uniforms remain the first and most effective line of defense.
Anti-ulcer effect of 3-[{2-(3,4-dimethox-yphenyl) carbamoyl} methyl]-amino--N-methy1 benzamide in experimental gastric and duodenal ulcers.
MIP-1145 is one of a family of proprietary, small molecule benzamide compounds that target melanin, a naturally-occurring pigment that is overexpressed in approximately 40 percent of melanomas.
Solazed is a proprietary, small molecule, benzamide compound that targets melanin, an oxygenated form of the amino acid tyrosine, which is over-expressed in approximately 40 percent of melanoma tumors.
Chidamide is an orally bioavailable, low-nanomolar inhibitor of cancer-associated histone deacetylase (HDAC) enzymes with favorable pharmacology and tolerability profiles relative to existing benzamide and non-benzamide HDAC inhibitors.
In addition, the Company disclosed that the structure of MGCD0103 which isa di-hydrobromide salt of a substituted 2-aminophenyl benzamide - a non-hydroxamate, inhibiting HDAC isoforms 1, 2, 3 and 11 as described in Poster C216.
an orally active benzamide type of class I-selective histone deacetylase (HDAC) inhibitor.