benzalkonium chloride


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benzalkonium chloride

 [ben″zal-ko´ne-um]
a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

ben·zal·ko·ni·um chlo·ride

(ben'zal-kō'nē-ŭm klōr'īd),
A mixture of alkylbenzyldimethylammonium chlorides in which the alkyls are long-chain compounds (C8 to C18); a surface-active germicide for many pathogenic nonsporulating bacteria and fungi. Aqueous solutions of this agent have a low surface tension, and possess detergent, keratolytic, and emulsifying properties that aid penetration and wetting of tissue surfaces.

benzalkonium chloride

/ben·zal·ko·ni·um chlo·ride/ (ben″zal-ko´ne-um) a quaternary ammonium compound used as a surface disinfectant and detergent, topical antiseptic, and antimicrobial preservative.

benzalkonium chloride

(bĕn′zăl-kō′nē-əm)
n.
A yellow-white powder prepared in an aqueous solution and used as a detergent, fungicide, bactericide, and spermicide.

benzalkonium chloride

a disinfectant and fungicide prepared in an aqueous solution in various strengths.

benzalkonium chloride

An antiseptic used in solution for skin and wound cleansing, as a means of sterilizing eye drops and contact lens solutions and as an ingredient in throat lozenges. Allergic reactions occur. Benzalkonium is included in Bradosol lozenges and, for external use only, in Conotrane, Dermol, Drapolene, Emulsiderm and Oilatum Plus.

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

benzalkonium chloride

a quaternary ammonium compound used as a surface disinfectant and detergent and as a topical antiseptic and antimicrobial preservative. See also zephiran.
References in periodicals archive ?
Distribution and disposition of benzalkonium chloride following various routes of administration in rats.
Corneal epithelial cellular dysfunction from benzalkonium chloride (BAC) in vitro.
5 Non-sensitizers benzalkonium chloride 5 NA vanillin 5 NA lactic acid 6 NA sodium dodecyl sulfate 6 NA N,N-diethyl-3-methylbenzamide NA NA 4-aminoacetanilide NA NA 4-acetamidoacetanilide NA NA 4-amino-2-methyl-acetanilide (j) NA NA 4-amino-3-methyl-acetanilide (j) NA NA 2,5-diacetaminotoluenej NA NA Chemical Murine GHS (LLNA) potency category EC3 ([micro]g/ [cm.
In vitro studies of antiglaucomatous prostaglandin analogues : Travoprost with and without benzalkonium chloride and preserved latanoprost.
m-1 at 25 C, these data were lower than that of BC12, BC14 or BC16, so the ADMDHAC, as a cationic surfactant, could be found much more application than that of benzalkonium chloride in some extent.
10) Numerous studies have revealed that there are deleterious corneal effects associated with benzalkonium chloride (BAC) that include destabilization of the tear film, death of corneal and conjunctival epithelial cells, morphological changes in the corneal epithelial cells, and reduction of the corneal epithelial barrier function.
Identification of benzalkonium chloride in commercial grapefruit seed extracts.
19) randomly assigned HIV-infected pregnant women in Cote d'Ivoire and Burkina Faso to either 1% benzalkonium chloride or placebo using a computer-generated system by block-randomisation.
Another substance that has been implicated in the development of rhinitis medicamentosa is benzalkonium chloride (BAC), an antimicrobial preservative often found in nasal sprays.
We investigated the effect of hemolysis on Pyrogallol Red (PYR) (2), benzethonium chloride (BTC) (3), and benzalkonium chloride (BC) (4) methods for measurement of protein.
The product contains four different antivirus components ethanol, benzalkonium chloride, polyoxyethylene alkylamine and polyhexamethylene biguanide (PHMB), and can remove not only general bacteria and viruses but also noroviruses that cause a fatal food poisoning.
Second, although not proved efficacious against cutaneous chytridiomycosis, the use of benzalkonium chloride, a recognized therapy for infections with non-hyphal fungi, failed to reduce mortality rates.