congenital hypertrophy of the retinal pigment epithelium

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congenital hypertrophy of the retinal pigment epithelium

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CHRPE

A thickening of the retinal pigment epithelium present at birth. The thickening appears on funduscopic examination as an oval, black, clearly demarcated lesion within which there are atrophic areas surrounded by a halo that has no pigment. It has been associated with and has been considered to be an ocular marker of familial adenomatous polyposis.

retinal pigment epithelium, congenital hypertrophy of the (CHRPE) 

A benign congenital proliferation of the retinal pigment epithelium which may appear unilaterally as a dark-grey or black, round or oval lesion in the fundus (typical form) or in other cases as multiple smaller lesions grouped together and resembling 'bear tracks'. In atypical form the lesions are bilateral. The latter is associated with familial adenomatous polyposis (an inherited condition characterized by neoplasms derived from epithelial tissue which appear as polyps throughout the rectum and colon and may become malignant) and its variants, Turcot syndrome (neuroepithelial tumours in the central nervous system) or Gardner's syndrome (soft tissue tumours).
References in periodicals archive ?
SNOW PLACE LIKE HOME: A Greenland Inuit outside his igloo; SLIPPERY BUSINESS: Hunter jumps across the ice in Greenland; COOL BLUE: Stunning shot taken inside an iceberg; MAGIC: Cherry and Brian; CHILLING: Adult American grey wolf defends his food with a snarl; ICE CATCH: Reindeer herder in Siberia; BIG FOOT: Inuit hunter checks polar bear tracks
They'll take you on a hike up a mountain to see bear tracks or to a city rooftop for their organic herb gardens.
The elk had turned the small spring seep into a muddy wallow, which was pockmarked by at least five different-sized bear tracks, including one of monstrous proportions.
Deputies, called to the area weeks before when Kelly's car was found there, had spotted footprints with bear tracks behind them.
With eyes sparkling, they showed me bear tracks in the soft earth of the creekbed and nourished my imagination with story after story.
I study bear tracks in damp sand beside a Canadian lake while whining swarms drill for chinks in my bug suit armor.
Deputies did find footprints with bear tracks behind them.
is inviting consumers to make tracks to its restaurants -- bear tracks, that is -- for a promotion sure to produce smiles at the end of the trail.
Even as McLellan took his guests around to check the trap line, he pointed out bear tracks alongside the tire tracks of logging trucks.
Old and flesh brown bear tracks littered the high-water mark, along with half-rotting salmon and piles of bear dung.
After a full day of marching under heavy packs we still encounter no bear tracks, no keta.
Bear tracks larger than a man's size 12 boot aren't uncommon along stream beds or threaded through the alder-thick ravines on Burton's ranch.