batrachotoxin


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Related to batrachotoxin: saxitoxin

ba·trach·o·tox·in

(ba-tra-kō-tok'sin),
A neurotoxin from the Colombian arrow poison frogs (Phyllobates spp.). It is nontoxic when ingested. If it is injected or if ulcers are present, it will cause an irreversible increase in permeability of sodium ions in nerve membrane, producing paralysis.
[G. batrachos, frog, + toxin]

batrachotoxin

(bə-trăk′ə-tŏk′sĭn, băt′rə-kō-)
n.
A steroid alkaloid derived from skin secretions of South American poison-dart frogs of the genus Phyllobates. It is one of the most potent venoms known.
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References in periodicals archive ?
The name batrachotoxin is derived from the Greek "batrachos," meaning frog.
Batrachotoxin blocks neuromuscular transmission irreversibly.
Batrachotoxins (BTX-A, batrachotoxin and homobatrachotoxin) can be identified using HPLC-MS and as dialkylpyrrole carboxylates (batrachotoxin and homobatrachotoxin) that can be detected by a sensitive Ehrlich's reaction.
Levels of batrachotoxin and lack of sensitivity to its action in Poison-Dart frogs (Phyllobates).
Batrachotoxin alkaloids from passerine birds: a second toxic bird genus (Ifrita kowaldft from New Guinea.
The batrachotoxins are "very rare compounds, and they occur spottily in nature," he says.
and their colleagues figured out in 1992 that the birds carry steroids called batrachotoxins, which were first identified in the 1960s as poisons in some frog skins.
Some other frog poisons have been traced to a dietary source, but batrachotoxins have remained a mystery in both birds and frogs.
It's still possible, although unlikely, that the birds and the beetles independently get batrachotoxins from some third source, says Dumbacher.
Batrachotoxins sabotage the sodium channels employed by nerve cells.