basophilic stippling

basophilic stippling

Etymology: Gk, basis + philein, to love; D, stippen, to prick

the presence of punctate blue nucleic acid remnants in red blood cells, observed under the microscope on a Wright-Giemsa-Gram-stained blood smear. Stippling is characteristic of lead poisoning. See also basophil, lead poisoning.

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stippling (stip´ling),

n 1. an orange-peel appearance of the attached gingiva, believed to result from the bundles of collagen fibers that enter the connective tissue papillae.
2. a roughening of the labial and buccal surfaces of denture bases to imitate the stippling of natural gingiva.

stippling, basophilic,

n See basophilia.

stippling, gingival,

n See gingiva, stippling.

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basophilic

staining readily with basic dyes.

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basophilic bone matrix

vitamin D poisoning causes the appearance of intensely basophilic bone matrix of a distincitive pattern.

basophilic cell

see basophil cell.

basophilic enterocolitis

one of the several types of enterocolitis causing chronic diarrhea in horses characterized by fibrinous and ulcerative typhlocolitis and basophilic infiltrates in the regional mucosa and submucosa.

basophilic leukemia

see leukemia.

basophilic rubricyte

a stage in cellular maturation of erythrocytes, between the prorubricyte and polychromatophilic rubricyte. Characterized by a narrow rim of dark blue cytoplasm and condensed nuclear chromatin in a 'cartwheel' pattern.

basophilic stippling

distinct or diffuse, fine to coarse, dark granular pattern in erythrocytes, representing aggregated ribosomes and caused by ineffective heme formation. Seen in lead poisoning, mainly in dogs and a characteristic of active erythropoiesis in sheep and cattle.

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stippling

a spotted condition or appearance, such as an appearance of the retina as if dotted with light and dark points, or the spotted appearance of the erythrocytes in basophilic stippling.

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basophilic stippling

see basophilic stippling.