basophil

basophil /ba·so·phil/ (ba´so-fil)

1. any structure, cell, or histologic element staining readily with basic dyes.

2. a granular leukocyte with an irregularly shaped, relatively pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size.

3. one of the hormone-producing basophilic cells of the adenohypophysis; types include gonadotrophs and thyrotrophs. basophil´ic

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ba·so·phil (bs-fl) or ba·so·phile (-fl)

n.

A cell, especially a white blood cell, having granules that stain readily with basic dyes.

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Basophil

White blood cell that increases in response to parasitic infections and allergic reactions.

Mentioned in: White Blood Cell Count and Differential

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basophil

[bā′səfil]

Etymology: Gk, basis + philein, to love

a granulocytic white blood cell characterized by cytoplasmic granules that stain blue when exposed to a basic dye. Basophils represent 1% or less of the total white blood cell count. The relative number of basophils increases in myeloproliferative diseases and decreases in severe allergic reactions. An increase in number is seen during the healing phase of inflammation. Basophils produce histamine during inflammatory reactions. Also called basophilic erythrocyte. Compare eosinophil, neutrophil. See also agranulocyte, differential white blood cell count, granulocyte, leukocyte, polymorphonuclear leukocyte. basophilic, adj.

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basophil [ba´so-fil]

1. any structure, cell, or histologic element staining readily with basic dyes.

2. a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size; about 1 per cent bring anticoagulants to inflamed tissues. Called also basophilic leukocyte.

3. one of the hormone-producing basophilic cells of the adenohypophysis; types include gonadotrophs and thyrotrophs. Called also beta cell.

basophilic.

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basophil,

n white blood cell with cytoplasmic granules and histamines used to direct other WBCs to inflamed areas.

Basophils.

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basophil (bā´sfil),

n See leukocyte.

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basophil

1. any structure, cell or histological element staining readily with basic dyes.

2. a granular leukocyte with an irregularly shaped, relatively pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size.

3. a beta cell of the adenohypophysis.

4. basophilic.

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basophil cell

a beta cell of the adenohypophysis which produces luteinizing and follicle stimulating hormones.

basophil degranulation test

an in vitro cellular test for immediate hypersensitivity; it detects degranulation of basophils, by their loss of affinity for staining, when blood from a hypersensitive dog is incubated with allergen extracts.

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basophil

Basophilic granulocyte Hematology A type of granular WBC with large distinctly basophilic/“blue” 2º granules containing heparin, histamine, PAF and other mediators of the immediate hypersensitivity response, which are released when IgE cross-links to the high affinity Fc receptors on the cell surface