basophil


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Related to basophil: eosinophil, monocyte, lymphocyte

basophil

 [ba´so-fil]
1. any structure, cell, or histologic element staining readily with basic dyes.
2. a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size; about 1 per cent bring anticoagulants to inflamed tissues. Called also basophilic leukocyte.
3. one of the hormone-producing basophilic cells of the adenohypophysis; types include gonadotrophs and thyrotrophs. Called also beta cell.

ba·so·phil

, basophile (bā'sō-fil, -fīl),
1. A cell with granules that stain specifically with basic dyes.
2. Synonym(s): basophilic
3. A phagocytic leukocyte of the blood characterized by numerous basophilic granules containing heparin, histamine, and leukotrines; except for its segmented nucleus, it is morphologically and physiologically similar to the mast cell although they originate from different stem cells in the bone marrow.
[baso- + G. philēo, to love]

basophil

/ba·so·phil/ (ba´so-fil)
1. any structure, cell, or histologic element staining readily with basic dyes.
2. a granular leukocyte with an irregularly shaped, relatively pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size.
3. one of the hormone-producing basophilic cells of the adenohypophysis; types include gonadotrophs and thyrotrophs. basophil´ic

basophil

(bā′sə-fĭl, -zə-) also

basophile

(-fīl′, -fĭl)
n.
A cell, especially a white blood cell, having granules that stain readily with basic dyes.

basophil

[bā′səfil]
Etymology: Gk, basis + philein, to love
a granulocytic white blood cell characterized by cytoplasmic granules that stain blue when exposed to a basic dye. Basophils represent 1% or less of the total white blood cell count. The relative number of basophils increases in myeloproliferative diseases and decreases in severe allergic reactions. An increase in number is seen during the healing phase of inflammation. Basophils produce histamine during inflammatory reactions. Also called basophilic erythrocyte.Compare eosinophil,neutrophil.See also agranulocyte,differential white blood cell count,granulocyte,leukocyte. basophilic, adj.
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Basophil

basophil

A type of granular leukocyte with large, distinctly basophilic/“blue” secondary granules containing heparin, histamine, platelet-activating factor (PAF) and other mediators of the immediate hypersensitivity response, which are released when IgE cross-links to the high-affinity Fc receptors on the cell surface.

basophil

Basophilic granulocyte Hematology A type of granular WBC with large distinctly basophilic/“blue” 2º granules containing heparin, histamine, PAF and other mediators of the immediate hypersensitivity response, which are released when IgE cross-links to the high affinity Fc receptors on the cell surface

ba·so·phil

, basophile (bā'sō-fil, -fīl)
1. A cell with granules that stain specifically with basic dyes.
2. Synonym(s): basophilic.
3. A phagocytic leukocyte of the blood characterized by basophilic granules containing heparin and histamine; except for its segmented nucleus, it is morphologically and physiologically similar to the mast cell, although the two cell types originate from different stem cells in the bone marrow.
[baso- + G. philēo, to love]

basophil

Having an affinity for alkali. The term is used conveniently to refer to the group of blood white cells (leukocytes) whose internal granules take up an alkaline stain. The granules in basophils are mainly histamine and it is the release of this powerful chemical that causes most of the trouble in allergy. Basophils closely resemble tissue MAST CELLS.

Basophil

White blood cell that increases in response to parasitic infections and allergic reactions.

basophil

a granular white blood cell (leukocyte) that takes up non-acidic stains

basophil,

n white blood cell with cytoplasmic granules and histamines used to direct other WBCs to inflamed areas.
Enlarge picture
Basophils.

ba·so·phil

, basophile (bā'sō-fil, -fīl)
A phagocytic leukocyte of the blood characterized by numerous basophilic granules containing heparin, histamine, and leukotrines.
[baso- + G. philēo, to love]

basophil (bā´səfil),

basophil

1. any structure, cell or histological element staining readily with basic dyes.
2. a granular leukocyte with an irregularly shaped, relatively pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm containing coarse bluish-black granules of variable size.
3. a beta cell of the adenohypophysis.

basophil cell
a beta cell of the adenohypophysis which produces luteinizing and follicle stimulating hormones.
basophil degranulation test
an in vitro cellular test for immediate hypersensitivity; it detects degranulation of basophils, by their loss of affinity for staining, when blood from a hypersensitive dog is incubated with allergen extracts.
References in periodicals archive ?
If female patients with CFS and MCS and HT-related autoantibodies are found to have functional anti-FceRla and low or even borderline low CI INH levels, the cumulative effect may be significant, and although female patients with hypersensitivities and ANA may have anti-FceRIa less able to induce, "pronounced histamine-releasing activity," from basophils (according to one study), there seems to be a possible link between ANA and C1 INH deficiency and/or autoantibodies.
WBC percentage of neutrophils, monocytes, lymphocytes, eosinophils, and basophils (data not shown)], linear regression revealed a statistically significant, positive relationship of endotoxin to absolute counts of monocytes, lymphocytes, and neutrophils in the overall study population (Table 2).
3]/[micro]L Heterophils, % 71 [+ or -] 13 74 35-85 Lymphocytes, % 23 [+ or -] 12 21 6-55 Eosinophils, % 0 [+ or -] 0 1 0-1 Monocytes, % 0 [+ or -] 0 0 0-3 Basophils, % 0 [+ or -] 0 0 0-5 Heterophil: lymphocyte 3.
Evaluation of blood parameters showed higher values of hemoglobin and hematocrit values and eosinophil and basophil counts in the Group I (Table-II).
In patients with IgG autoantibodies against IgE or Fc[epsilon]RI, the depletion of mast cell-bound IgE by omalizumab and consequent downregulation of Fc[epsilon]RI on mast cells and basophils, the concentration of complexes of Fc[epsilon]RI-IgE on mast cells/basophils decreases (12);
The positive basophil activation assay or basophil activation test (BAT), which was also associated with NCWS, has previously been demonstrated as a highly specific tool for food allergy including CM allergy.
Mast cells, along with basophils and eosinophils, are classed as granulocytes because they all contain these packets of preformed mediators.
2010; 2011) reported QTL for TLR9, an immunity related element in gut, at 0 to 47 cM and for IFNG at 47 to 93 cM on SSC16 in a Duroc x Pietrain cross, where the QTL for basophil was also detected at 42 Mb in this study (Table 3).
IgG is a sign of exposure in food allergies; however, only a few allergens have been evaluated and cut-off values determined (28) Cell activation test Basophil activation test (BAT) mimics in vitro contact of allergen and circulating basophils.
Yogurt and garlic groups remained statistically insignificant in increasing Eosinophils, Basophil and Monocyte population both at treatment and levels which resemble with the study of Farinu et al.
05) differences in the basophil percentages amongst the chickens of groups A (0.
We proposed to identify the meaning of elevated basophil counts with the XE-2100.