Disease severity and basopenia were risk factors for the requirement of high-dose H1-antihistamines.
Eosinophilia (>400/|[mu]L) was found in 43 patients and basopenia (<20[mu]L) was found in 55 (23.
In addition, the risk factors related with H1-AH unresponsiveness were found as severity of urticaria and basopenia in our study.
Various abnormalities in basophils of chronic urticaria patients have been reported like basopenia
, paradoxical suppression of FceRI-mediated release of histamine from basophils, imbalance between positive and negative regulators of signaling through FceRI.
vivax), parasitosis intestinal y desnutricion cronica, tuvieron antes del tratamiento anemia homogenea normocitica, de grado leve, que se recupero en 30 dias a partir del tratamiento antimalarico; 80% tambien tuvieron trombocitopenia; el leucograma mostro, al dia 1, neutropenia y basopenia, con eosinofilia, junto con linfocitos normales y monocitopenia marcada.
vivax), intestinal parasites and chronic malnutrition, had anemia (mild, homogeneous, normocytic) before therapy, but they recovered from it in 30 days after effective antimalarial treatment; 80% also suffered from thrombocytopenia; at day 1, they showed neutropenia, basopenia, and eosinophilia, along with normal lymphocytes and severe monocytopenia.