Grade 0: no reaction or <10% reactivity in tumour cells; grade 1+: weak reactivity >10% of the tumour cells; with reactivity only in part of the membrane; grade 2+: moderate reactivity in >10% of the cells, with staining across the lateral and basolateral
membrane; grade 3+: strong reactivity with intense staining of the lateral and basolateral
membrane in >10% of the cells.
HER2 expression in gastric and gastroesophageal junction adenocarcinomas can be complete, basolateral
, or lateral membranous staining, (70) which differs from HER2 expression in breast carcinoma cells, where only complete membranous staining counts.
The research revealed that an incoming memory trace is actually deposited simultaneously in the hippocampus and the neocortex--as well as in the basolateral
amygdala, a repository for memories' emotional associations.
Intestinal glucose absorption is mediated by the sodium-dependent glucose transporter SGLT1, whereas the facilitated glucose transporter GLUT2 provides a basolateral
glucose exit into the blood stream (Roder et al.
This volume collects 17 articles on the molecular mechanisms involved in establishing and maintaining cell polarity, as well as their relevance for human disorders, focusing on eukaryotes and epithelial cells and how polarity mechanisms facilitate the development of their apical and basolateral
surfaces, tube formation, exchange of waste and nutrients, and the generation and maintenance of specialized structures at the cell surface.
After entering enterocytes, iron can be used for metabolic purposes, stored within intracellular ferritin, or exported across the basolateral
membrane through ferroportin-1 (Fpn1) into the bloodstream.
The associated memory cells that fired at the time - in three different parts of the brain, the hippocampus, the prefrontal cortex and the basolateral
amygdala, which stores emotional associations of memories - were labeled.
It is mentioned that NIS protein must be expressed in basolateral
membranes of thyroid follicular epithelium in order to function (7, 8).
Adenylate kinase (AK)-based cytotoxicity assay AK activity was measured in the basolateral
medium of the cultures (as a cross-sectional sampling at various time points post-exposure) using a BioVision Bioluminescence Cytotoxicity Assay Kit (BioVision, Inc.
In addition, alcohol has been found to promote secretion of digestive enzymes from the basolateral
aspect of the acinar cell via mechanisms involving protein kinase C (Cosen-Binker 2007).
Inflammation up-regulates Hepcidin, the primary hepatic iron absorption regulating protein, which inhibits the activity of Ferroportin at the intestinal basolateral
cell membrane to transport iron out of storage for utilization.
Se administro propranolol en la region central y basolateral
de la amigdala luego de la presentacion del sabor novedoso (Bahar, Samuel, Hazvi, & Dudai, 2003).